Journal of Basic and Applied Pharmacology https://li01.tci-thaijo.org/index.php/JBAP <p><span style="font-size: medium;"><strong>Journal of Basic and Applied Pharmacology</strong> <strong>(J Basic App Pharmacol) </strong>(former title: Thai Journal of Pharmacology) is a peer-reviewed journal publishing original research articles, reviews, case reports, letters to editors and commentaries on pharmacology and related fields, i.e. pharmacodynamics, pharmacokinetics, pharmacotherapeutics, toxicology, clinical pharmacology, molecular pharmacology, pharmacogenetics/pharmacogenomics, comparative pharmacology, safety pharmacology, systems pharmacology, pharmacoepidemiology and ethnopharmacology. The research article and review of all fields must be peer-reviewed by at least three reviewers. Thai Journal of Pharmacology has been abstracted and indexed by <strong>Thai Journal Citation Index (TCI - Tier 1)</strong> and <strong>ASEAN Citation Index (ACI)</strong>. The indexing in the TCI and ACI is continued with the <strong>Journal of Basic and Applied Pharmacology.</strong></span><span style="font-size: medium;"><strong><br /></strong></span></p> <p> </p> <p><span style="font-size: medium;"><strong>ISSN: 2774-0854 (Online)</strong></span></p> en-US <p>Upon acceptance of an article, the&nbsp;Pharmacological and Therapeutic Society of Thailand will have exclusive right to publish and distribute the article in all forms and media and grant rights to others. Authors have rights to use and share their own published articles.</p> jbap@nu.ac.th (Professor Dr. Kesara Na-Bangchang) rattima@nu.ac.th (Assoc.Prof. Rattima Jeenapongsa) Sat, 21 Sep 2024 23:18:43 +0700 OJS 3.3.0.8 http://blogs.law.harvard.edu/tech/rss 60 Effects of Feeding Unripe Plantain Peel Meal on Haematological Parameters and Serum Bio-Chemicals of Growing Broilers https://li01.tci-thaijo.org/index.php/JBAP/article/view/262794 <p>Plantain peel has been reported to be rich in minerals and high in energy. These potentials have qualified it to be a research focus as a non-conventional energy source for the preparation of feed for broilers. It was on this background that this experiment was conducted for 6 weeks with eighty-four (84) day old broiler chicks. They were grouped into treatments and replicates at 2 weeks having attained an average weight range of 325.56±2.70 to 329.90±10.06 g to assess the effects of 0, 5, 10, and 20% maize replaced by unripe plantain peel meal (UPPM) in the chickens’ diet on their haematological parameters and serum bio-chemicals. The birds were assigned to each of the treatments replicated three times to contain seven birds per replicate using a completely randomized design (CRD). There were no significant differences (p&gt;0.05) in the haematological parameters viz; erythrocyte sedimentation rate, packed cell volume, red blood cell count, haemoglobin concentration, mean corpuscular volume, mean corpuscular haemoglobin, mean corpuscular haemoglobin concentration, lymphocytes, heterophils, monocytes, basophils, and eosinophils. The treatment significantly influenced liver function enzymes, high-density lipoprotein, and some metabolites (p &lt; 0.05). ALP increased following an increase in the inclusion of UPPM in the diets but was within the normal recommended range. Cholesterol, high-density lipoprotein, and triglycerides were highest in the control; suggesting their serum lowering potential by UPPM which may translate to lowering the risk of cardiovascular disease and high blood pressure. The antioxidant assays revealed an upward rise in superoxide dismutase (SOD) following an increased percentage inclusion of UPPM. Following the outcome of this study, the recommendation of further research on UPPM in broilers’ nutrition was made. This may eventually lead to the discovery of a novel natural source of antidyslipidaemic, antihypercholesterolemic, and antioxidant agents from UPPM.</p> Joseph Olowo Arogbodo, Festus Igbe, Isaac Adebayo Copyright (c) 2024 Journal of Basic and Applied Pharmacology https://creativecommons.org/licenses/by-nc-nd/4.0 https://li01.tci-thaijo.org/index.php/JBAP/article/view/262794 Sat, 21 Sep 2024 00:00:00 +0700 Evaluating the Impact of Blended Learning in Clinical Pharmacology Among Medical and Allied Health Undergraduates: A Cross-Sectional Study https://li01.tci-thaijo.org/index.php/JBAP/article/view/264097 <p><strong>Objective:</strong> This study evaluated the effectiveness of a blended learning model in teaching clinical pharmacology to undergraduate healthcare students, including those from medical and allied health disciplines. The study assessed the model’s impact on their career development and examined its effects on academic performance, knowledge retention, practical application of pharmacological concepts, career aspirations, and clinical practice readiness.</p> <p><strong>Methods:</strong> A cross-sectional survey was conducted from April 10 to May 20, 2024, in China. Undergraduate healthcare students who completed a clinical pharmacology course via blended learning participated. Data were collected using an online questionnaire through “Questionnaire Star”. Out of 513 collected questionnaires, 330 valid responses were analyzed using IBM SPSS Statistics and Python for descriptive statistics, correlation, regression, and cluster analyses.</p> <p><strong>Results:</strong> The blended learning model significantly enhanced student engagement and knowledge acquisition. The Flipped Classroom was the most frequently used method (average frequency 0.75), followed by Face-to-Face Teaching (0.71) and Online MOOC Learning (0.68). Both male and female students reported similar knowledge impact (4.08±0.93 for males, 4.00±0.90 for females). Clinical Medicine students reported the highest satisfaction (4.44±0.66). Regression analysis identified Online MOOC Learning (0.260) and Face-to-Face Teaching (0.201) as significant predictors of knowledge acquisition. Cluster analysis revealed three distinct student groups with varying satisfaction and perceived effectiveness.</p> <p><strong>Objective:</strong> This study evaluated the effectiveness of a blended learning model in teaching clinical pharmacology to undergraduate healthcare students, including those from medical and allied health disciplines. The study assessed the model’s impact on their career development and examined its effects on academic performance, knowledge retention, practical application of pharmacological concepts, career aspirations, and clinical practice readiness.</p> <p><strong>Methods:</strong> A cross-sectional survey was conducted from April 10 to May 20, 2024, in China. Undergraduate healthcare students who completed a clinical pharmacology course via blended learning participated. Data were collected using an online questionnaire through “Questionnaire Star”. Out of 513 collected questionnaires, 330 valid responses were analyzed using IBM SPSS Statistics and Python for descriptive statistics, correlation, regression, and cluster analyses.</p> <p><strong>Results:</strong> The blended learning model significantly enhanced student engagement and knowledge acquisition. The Flipped Classroom was the most frequently used method (average frequency 0.75), followed by Face-to-Face Teaching (0.71) and Online MOOC Learning (0.68). Both male and female students reported similar knowledge impact (4.08±0.93 for males, 4.00±0.90 for females). Clinical Medicine students reported the highest satisfaction (4.44±0.66). Regression analysis identified Online MOOC Learning (0.260) and Face-to-Face Teaching (0.201) as significant predictors of knowledge acquisition. Cluster analysis revealed three distinct student groups with varying satisfaction and perceived effectiveness.</p> <p><strong>Conclusion: </strong>The blended learning model effectively enhances academic performance, knowledge retention, and professional skills among undergraduate medical and allied health students. A balanced integration of online and offline components maximizes learning outcomes. Tailored approaches are needed for different disciplines. Future research should focus on longitudinal studies to assess the long-term impact on career development.</p> Beibei Ye, Lanjie Huang, Keyi Peng, Yang Liu, Xin Chen, Bingliang Li, Ji Li, Jian Yang Copyright (c) 2024 Journal of Basic and Applied Pharmacology https://creativecommons.org/licenses/by-nc-nd/4.0 https://li01.tci-thaijo.org/index.php/JBAP/article/view/264097 Mon, 11 Nov 2024 00:00:00 +0700