A Preliminary Study on the Efficacy of Albendazole against Haplorchis taichui: an Intestinal Trematode

Abstract

Abstract

The efficacy of albendazole in treating an intestinal fluke, Haplorchis taichui, was studied in experimental mice. At a dose of 40 mg per mouse, a 100% cure rate was obtained with five experimentally-infected mice. In five control mice, the infection rates were 27.1, 38.5, 31.4, 17.1, and 44.2%, respectively. The result showed that albendazole could cure intestinal fluke infection. Further analysis is needed in humans with co-infection of intestinal roundworms and flukes.