Main Article Content
Background and Objective: Chronic kidney disease is a major public health problem in Thailand and trend to be increasing every year. Patients with chronic kidney disease have to pay a big amount of budget for treatment each year. The objective of this study was to study the effectiveness of treatment of patients with glomerular disease by considered kidney biopsy pathology reported, patients clinical, and laboratory blood and urine examination reports.
Methods: This study were collected data from medical records of 38 patients with glomerular disease and got kidney biopsy and treatment at Roi Et hospital during January 1, 2015 to December 31, 2018 and considered for kidney biopsy pathology reported, patients clinical, and laboratory blood and urine examination reports. Statistical analyses were used descriptive statistics and paired t-test.
Results: Of 38 cases most of them were male 68.31 %, mean age 38. 37±15.54, body mass index between 18.5-22.9 kg/m2 (50.00%), diabetes mellitus 42.11%, and hypertension 20.15%. Most of pathological reported were Lupus nephritis class IV 18.42%, and Immunoglobulin A nephropathy18.42%. After 6 months of surgery follow up the results showed that the found Creatinine mean was 1.11± 2.47 mg/dl, Estimated glomerular filtration rate (eGFR) mean was 74.59±42.18, Albumin mean was 3.66±0.75 mg/dl, Cholesterols mean was 203.13±75.67 mg/dl and Urine protein to creatinine ratio (UPCR) mean was 1.20±1.97g/gCr. The comparison of blood chemical tests between before and after 6 months surgery cholesterols level was found decreased significantly (p <0.001).
Conclusion: Overall patients with glomerular disease after treatment were clinical getting better and after 6 months of surgery cholesterols level was significantly decreases.
2. คนเชียงรายไตวายสูงรองจากกรุงเทพฯ - Thaihealth.or.th | สำนักงานกองทุนสนับสนุนการสร้างเสริมสุขภาพ (สสส.) [Internet]. Thaihealth.or.th. [cited 2019 Feb 26]. Available from: http://www.thaihealth.or.th/Content/46330-คนเชียงรายไตวายสูงรองจากกรุงเทพฯ.html
3. Senanayake S, Gunawardena N, Palihawadana P, Suraweera C, Karunarathna R, Kumara P. Depression and psychological distress in patients with chronic renal failure: Prevalence and associated factors in a rural district in Sri Lanka. J Psychosom Res 2018;112:25–31.
4. Jia X-B, Hou X-H, Ma Q-B, Cai X-W, Li Y-R, Mu S-H, et al. Assessment of renal function and risk factors for chronic kidney disease in patients with peripheral arterial disease. Angiology 2017 ; 68: 776–81.
5. Pavkov ME, Harding JL, Chou C-F, Saaddine JB. Prevalence of diabetic retinopathy and associated mortality among diabetic adults with and without chronic kidney disease. Am J Ophthalmol 2019; 198: 200–8.
6. Park Y-H, Shin JA, Han J-H, Park Y-M, Yim HW. The association between chronic kidney disease and diabetic retinopathy: the Korea National Health and Nutrition Examination Survey 2008-2010. PloS One 2015; 10: e0125338.
7. Young BA, Katz R, Boulware LE, Kestenbaum B, de Boer IH, Wang W, et al. Risk factors for rapid kidney function decline among african americans: The Jackson Heart Study (JHS). Am J Kidney Dis 2016; 68: 229–39.
8. Damtie S, Biadgo B, Baynes HW, Ambachew S, Melak T, Asmelash D, et al. Chronic kidney disease and associated risk factors assessment among diabetes mellitus patients at A Tertiary Hospital, Northwest Ethiopia. Ethiop J Health Sci 2018; 28: 691–700.
9. Lin C-Y, Hsieh M-C, Kor C-T, Hsieh Y-P. Association and risk factors of chronic kidney disease and incident diabetes: a nationwide population-based cohort study. Diabetologia 2019; 62: 438–47.
10. Liu H-W, Tsai W-H, Liu J-S, Kuo K-L. Association of vegetarian diet with chronic kidney disease. Nutrients 2019; 11: 236-45
11. Kanjanabuch T, Kittikovit W, Lewsuwan S, Leelahavanichkul A, Avihingsanon Y, Praditpornsilpa K, et al. Etiologies of glomerular diseases in Thailand: a renal biopsy study of 506 cases. J Med Assoc Thai 2005; 88: S305-311.
12. Covic A, Schiller A, Volovat C, Gluhovschi G, Gusbeth-Tatomir P, Petrica L, et al. Epidemiology of renal disease in Romania: a 10 year review of two regional renal biopsy databases. Nephrol Dial Transplant 2006 ; 21: 419–24.
13. Rychlík I, Jancová E, Tesar V, Kolsky A, Lácha J, Stejskal J, et al. The Czech registry of renal biopsies.Occurrence of renal diseases in the years 1994-2000. Nephrol Dial Transplant 2004;19: 3040–9.
14. Rivera F, López-Gómez JM, Pérez-García R, Spsnish Registry of Glomerulonephritis. Frequency of renal pathology in Spain 1994-1999. Nephrol Dial Transplant 2002; 17: 1594–602.
15. Garau M, Cabrera J, Ottati G, Caorsi H, Gonzalez Martinez F, Acosta N, et al. Temporal trends in biopsy proven glomerular disease in Uruguay, 1990-2014. PloS One 2018; 13: e0206637.
16. Shin HS, Cho DH, Kang SK, Kim HJ, Kim SY, Yang JW, et al. Patterns of renal disease in South Korea: a 20-year review of a single-center renal biopsy database. Ren Fail 2017; 39: 540–6.
17. Xu X, Ning Y, Shang W, Li M, Ku M, Li Q, et al. Analysis of 4931 renal biopsy data in central China from 1994 to 2014. Ren Fail 2016 ; 38: 1021–30.
18. Zhang X, Liu S, Tang L, Wu J, Chen P, Yin Z, et al. Analysis of pathological data of renal biopsy at one single center in China from 1987 to 2012. Chin Med J (Engl) 2014; 127: 1715–20.
19. Parichatikanond P, Chawanasuntorapoj R, Shayakul C, Choensuchon B, Vasuvattakul S, Vareesangthip K, et al. An analysis of 3,555 cases of renal biopsy in Thailand. J Med AssocThai 2006; 89: S106-111.