https://li01.tci-thaijo.org/index.php/TBPS <p><strong>Thai Bulletin of Pharmaceutical Sciences</strong> is a peer-reviewed journal published by Faculty of Pharmacy, Silpakorn University, Thailand. The Journal publishes original articles and review articles addressing topics in Pharmacy, Pharmaceutical Sciences, Medical Sciences and Health Sciences. All submitted manuscripts must be reviewed by at least three reviewers through a double-blind peer-review system. Two issues are published online per year.</p> en-US <p>All articles published and information contained in this journal such as text, graphics, logos and images is copyrighted by and proprietary to the Thai Bulletin of Pharmaceutical Sciences, and may not be reproduced in whole or in part by persons, organizations, or corporations other than the Thai Bulletin of Pharmaceutical Sciences and the authors without prior written permission.</p> [email protected] (Assoc. Prof. Theerasak Rojanarata, Ph.D.) [email protected] (Ms. Jiraporn Boonchu) Wed, 21 Feb 2024 00:00:00 +0700 OJS 3.3.0.8 http://blogs.law.harvard.edu/tech/rss 60 https://li01.tci-thaijo.org/index.php/TBPS/article/view/261135 <p>Hospitalized patients are prone to medication errors (MEs) which usually occur at transition points during care. Communication problems or the transfer of information between patients and healthcare professionals are among the causes of MEs. This study developed a medication reconciliation system with pharmacists who were specifically responsible for identification of medication discrepancy and intervention. This action research on patient admissions at Songklanagarind Hospital between October 2018 - September 2022 is divided into 4 phases: 1. Designed and developed medication reconciliation system with pharmacists in collaboration with a multidisciplinary team. 2. Conducted trial with one pharmacist and piloted it among patients with a previous history of using warfarin. 3. Developed medication reconciliation program. <span style="font-size: 0.875rem;">4. Expanded the program to patients who are at risk of MEs by increasing the number of pharmacists to two. 70-78% of patients had medication reconciliation processed by a pharmacist within 24 hours of hospital admission. Pharmacists found MEs of 11-17%, with the most common being the incorrect dosage or frequency of medication (50-70%), followed by omission (15-45%). In 70-77% of the MEs, the medication did not reach the patient. Pharmacists have an important role in preventing MEs by reconciling medications. Through the medication reconciliation process, pharmacists can assess the completeness and accuracy of medication lists to reduce MEs and prevent those errors from affecting patients.</span></p> <p> </p> piengjai kiettanawattana Copyright (c) 2024 Thai Bulletin of Pharmaceutical Sciences https://li01.tci-thaijo.org/index.php/TBPS/article/view/261135 Sun, 03 Mar 2024 00:00:00 +0700 https://li01.tci-thaijo.org/index.php/TBPS/article/view/261085 <p>Pikad Trisukkhati Samutharn (PTS) is a medicinal formula used in Thai traditional medicine for treating severe fever, inflammation, and diarrhea, as well as for general health promotion. This herbal formula was made from the roots of three plants: <em>Oroxylum indicum</em> (L.) Kurz, <em>Sesbania grandiflora</em> (L.) Pers and <em>Ficus racemosa</em> L. The purpose of this study was to investigate the antioxidation activity and chemical profiling of PTS and its herbal components. The antioxidation activity of the extracts was determined using the DPPH free radical scavenging assay, as well as the Folin-Ciocalteu method, to investigate the total phenolic contents. The thiobarbituric acid reactive substance (TBAR) assay was used to test lipid peroxidation activity. The chemical profiling of PTS was demonstrated using gas chromatography–mass spectrometry (GC-MS) analysis. The results revealed that the total phenolic content of the ethanolic extract (79.57 ± 2.33 mg GAE/g extract) was greater than that of the aqueous extract (12.55 ± 2.83 mg GAE/g extract) of the PTS. The DPPH free radical scavenging activity of the PTS ethanolic extract (IC₅₀ value 80.69 ± 0.40 mg/mL) was also stronger than that of the PTS aqueous extract (IC₅₀ value <br />650.10 ± 98.20 mg/mL). Lipid peroxidation of the PTS ethanolic extract was moderate with 32.47 ± 0.71% inhibition. GC-MS revealed the presence of several phenolic compounds contained in the PTS ethanolic extract in which the identified compounds had previously been reported to have several pharmacological activities such as antioxidation, anti-inflammation, and antimicrobial. In conclusion, the antioxidation and chemical constituents of the PTS extract were demonstrated for the first time, and more pharmacological activities of PTS should be explored to confirm its traditional use.</p> Nattiya Chaichamnong, Prapapan Temkitthawon, Nuntika Prommee, Ninnart Intharit, Jittiporn Chaorai, Nattanan Sasong, Ngamrayu Ngamdokmai, Kornkanok Ingkaninan Copyright (c) 2024 Thai Bulletin of Pharmaceutical Sciences https://li01.tci-thaijo.org/index.php/TBPS/article/view/261085 Wed, 21 Feb 2024 00:00:00 +0700