@article{Sam-ang_Surangkul_Savaspun_Phanumartwiwath_2020, place={Bangkok, Thailand}, title={Antioxidant and acetylcholinesterase inhibitory activities of Morinda citrifolia L. extracts}, volume={54}, url={https://li01.tci-thaijo.org/index.php/anres/article/view/242181}, abstractNote={<p>RESOURCESExtractions of roots, leaves and stems of Morinda citrifolia L. were carried out by maceration using ethanol, 40% ethanol/water and water, respectively. The aqueous leaf extract, ethanolic stem extract and aqueous root extract were obtained with highest percentage yields of 10.92%, 3.92% and 6.37% dry weight, respectively. The bioactivities of all the crude extracts were evaluated regarding their antioxidant and anti-acetylcholinesterase (AChE) activities. The crude ethanolic extract from roots had the relatively highest antioxidant activity with a half maximal inhibitory concentration (IC50) value of 5.97 mg/mL and total phenolic contents of 13.33 mg gallic acid equivalent/g crude extract. Moreover, the ethanolic root extract also had the most potent anti-AChE inhibitory activity with an IC50 value of 454 μg/mL. This study indicated that ethanolic M. citrifolia root extract should be a good candidate for AChE inhibitors which may be applied as herbal supplements for the prevention of Alzheimer’s disease.<br>online</p>}, number={2}, journal={Agriculture and Natural Resources}, author={Sam-ang, Pornpat and Surangkul, Damratsamon and Savaspun, Kongdech and Phanumartwiwath, Anuchit}, year={2020}, month={Apr.}, pages={173–179} }