Princess of Naradhiwas University Journal

Skin Moisturizing Efficacy of Hand Cleansing Gel Containing Cissampelos pareira Leaves Extract

Anucha Taiwong — 2025-11-21

Background and Objectives Cissampelos pareira leaves are a traditional herbal plant, but their utilization in cosmetics is quite limited. This study aimed to extract C. pareira leaves, develop gel formulations, evaluate their stability, and evaluate the moisturizing efficacy of hand sanitizer gel containing moisturizing agents from C. pareira leaves.

Methods The experimental research, a total of 30 participants were selected by purposive sampling. The data collection was obtained through the measurement of skin moisture using a Moist Sense® and assessing participants’ satisfaction after utilizing the products.

Results The results showed that polysaccharides extracted from C. pareira leaves yielded 30.45 ± 1.18% of dry plant weight. Following the preparation of the gel, it was found that all formulas were successfully developed into gel forms. F1 and F2 formulas demonstrated good stability under accelerated conditions. The F2 formula was identified as the most suitable due to its favorable texture and moderate color; therefore, it was selected for further efficacy testing. The result showed that the F2 formula was not contaminated by four pathogenic microorganisms and exhibited 99.99% bactericidal efficacy against Pseudomonas aeruginosa and Staphylococcus aureus within one minute. In relation to the effectiveness of moisturizing properties, skin hydration levels significantly increased at 15, 30, 60, 90, and 120 minutes after application compared to baseline values (p < 0.05). Furthermore, the test formula showed significantly higher average skin moisture content than the control formulation at all measurement periods (p < 0.05). In addition, participants reported a high level of satisfaction with both the test and control formula.

Conclusion and Recommendation Hand cleansing gel containing C. pareira leaves extract is effective in maintaining moisture. The extract should be utilized in developing formulations for other moisturizing products.

Development of a Prevention Model for Ventilator-Associated Pneumonia in Intensive Care Unit Patients at Thabo Crown Prince Hospital, Nong Khai Province

Patcharaporn Saengprom — 2025-11-21

Background and Objectives Patients who undergo endotracheal intubation and mechanical ventilation are approximately 3–20 times more likely to develop pneumonia than general patients. Continuous surveillance and infection prevention are therefore essential, particularly for professional nurses who play a critical role in patient care. This study aimed to investigate the current situation, develop a model, and evaluate the effectiveness of a pneumonia prevention model for mechanically ventilated patients in the intensive care unit at Thabo Crown Prince Hospital, Nong Khai Province.

Methods The research and development were conducted between January 2024 and June 2025 and consisted of three phases: 1) Studying the current situation and needs through a document review and qualitative research involving 10 registered nurses and 4 internists; 2) Developing the model; and 3) Examining the effectiveness of the model. The research instruments were validated by three experts, yielding an Index of Item-Objective Congruence (IOC) ranging from 0.67 to 1.00. The instruments used included the TIH2E Model, an infection data record form, a satisfaction evaluation form, and an observation form for model implementation. A one-group pretest-posttest quasi-experimental design was employed. The study sample consisted of 23 registered nurses and 34 patients on mechanical ventilation. Data were analyzed using descriptive statistics and the one-sample t-test.

Results A retrospective review (2021–2023) revealed an increasing trend of ventilator-associated pneumonia: VAP incidence. Nursing practice in VAP bundle implementation was incomplete and lacked continuous monitoring. The TIH2E Model comprised: 1) Team (multidisciplinary team), 2) Implementation, 3) Health education (for caregivers), 4) Environment (environmental management), and 5) Evaluation (monitoring and evaluation). After implementation, 76.50 % of patients did not develop VAP. Nurses reported satisfaction levels exceeding 80 %, and adherence to the model was greater than 95 %, with statistically significant improvement (p < .001).

Conclusions and Recommendations The TIH2E Model proved effective in enhancing nursing practices and reducing ventilator-associated pneumonia among mechanically ventilated patients. The model contributes to improved quality of care and patient safety.

The Effects of Transitional Nursing Program from Hospital to Home on Self-Care Behaviors and Readmission Rates among Older Adult Patients with Pneumonia

Hassana Whanprarat — 2025-11-21

Background and Objective Pneumonia is a major cause of hospital readmission and mortality among older adults. Transitional care nursing plays an important role in ensuring continuity of care after hospital discharge. This study aimed to examine the effects of a transitional care nursing program from hospital to home on self-care behaviors and readmission rates among older adult patients with pneumonia.

Methods This study was quasi-experimental. The participants were 52 older adults who were admitted to a general hospital in southern Thailand. They were divided equally into two groups: an experimental group and a control group, each comprising 26 participants. The research instruments consisted of a transitional care nursing program, a readmission record form, and a self-care behavior assessment tool, which was reviewed by five experts, yielding a content validity index (CVI) of 0.98 and a Cronbach’s alpha coefficient of 0.98. Data were analyzed using descriptive statistics, paired t-tests, independent t-tests, and chi-square tests.

Results The findings revealed that the experimental group had significantly higher self-care behavior scores after receiving the program, with statistically significant differences from both their pre-intervention scores and the control group (p < 0.01). Moreover, no participants in the experimental group were readmitted within 28 days post-discharge, whereas the control group had a 15.4% readmission rate.

Conclusion and Recommendations The findings of this study indicate that the transitional care nursing program effectively promotes self-care behaviors and reduces hospital readmission rates. It is considered appropriate for implementation in the care of older adults with pneumonia.