Kalasin University Journal of Science Technology and Innovation

Current Research On Pharmacological and Toxicological of Croton tiglium Linn.

Ronnachai Poowanna — 2024-08-26

Croton tiglium L., commonly known as Purging Croton and classified under the Euphorbiaceae family, has been traditionally used in Thai medicine as a potent purgative to treat colic, asthma, cough, phlegm, lymphatic disorders, cathartic, blood disorders, and parasitic infections. The seeds of Croton tiglium are incorporated in various formulations for treating symptoms resembling cancer. The chemical composition of the seeds includes oil (30.00-56.00%), carbohydrates (16.15%), proteins (16.00%), fibers (8.25%), and ash (3.60%). Key chemical constituents of the seeds are phorbol esters such as Phorbol-12-myristate-13-acetate, along with alkaloids, fatty acids, and amino acids. Phorbol esters exhibit a range of pharmacological activities, including antifungal, antiviral, antibacterial, laxative, vaccine adjuvant and anti-inflammatory properties. Notably, they demonstrate significant anticancer properties, effectively inhibiting the growth of cancer cells, including liver cancer, leukemia, lung cancer, prostate cancer, breast cancer, and gastric cancer. The inhibitory concentrations (IC₅₀) of these compounds are typically within the micromolar range. Despite its medicinal potential, the presence of phorbol-12-myristate-13-acetate (PMA) poses a major drawback due to its toxicity and role as a tumor promoter. Various methods have been developed to reduce the toxicity of Croton tiglium seeds, effectively lowering PMA levels. However, comprehensive data on the reduction of carcinogenic promotion activity is still lacking. If these detoxification methods can be proven to effectively reduce both PMA levels and its carcinogenic promotion activity, Croton tiglium could emerge as a promising herbal alternative for cancer treatment. Recent discoveries highlight the potential of phorbol esters as Protein kinase C (PKC) activators that inhibit specific PKC isoforms linked to cancer inhibition. The development of cancer therapies targeting specific PKC isoforms is currently a significant area of interest.

The Developing Online chemical service workflow tracking system

Supon Bokum — 2024-08-08

This research aims to 1) study the problem of traditional services in requesting the use of chemicals in the laboratory 2) develop a chemical service system that can track work flows online and 3) study the efficiency of reducing steps work, reduce time, and evaluate satisfaction in using online programs. By holding participatory workshops of laboratory workers to obtain information to design and develop programs. Program development tools use MySQL database management system. Font End display uses PHP, HTML 5, CSS3, Javascript. Back End uses MySQL, PHP, Database management uses HeidiSQL. and use the satisfaction assessment form for using the system. Results of the study of problems in traditional service provision That causes delays and the process cannot be traced. The main reason is the procedure has several steps. and using paper forms which makes services inconvenient After changing to a service system with a newly developed program, work steps can be inspected and tracked online. By adding a colored status bar to notify the status via email and LINE, it increases convenience for service users. Reduce working time Reduce paper use Data is recorded automatically. In terms of efficiency in reducing work steps and reducing time, it was found that work steps could be reduced by 3 steps out of 9 steps, reducing the waiting time of work steps as a percentage of waiting time reduction up to 84.38 – 85.13. And the results from the satisfaction assessment from the user group were at a good level. The total average satisfaction score was 4.19 with a standard deviation of 0.84.

Chili Spur Pepper Detection Model Developing for Sorting Machine

Watcharapon Hantongdee — 2024-08-26

Faculty of Science at Sriracha, Kasetsart University Siracha Campus, located in an industrial and agricultural area, aims to advance the agricultural industry through the application of computer technology. This research focuses on improving the sorting process for chili spur peppers by utilizing deep learning techniques such as YOLO to develop a model that accurately analyzes and sorts of peppers by color. The model is intended to enhance sorting processes in production lines and packaging within the agricultural industry. Researchers applied the YOLO technique, collecting 294 images of chili spur peppers and evaluating the model's performance using metrics such as Precision, Recall, and Mean Average Precision (mAP). The results demonstrated a high accuracy, with an average Precision of 99.6%. The study also evaluated the model's practical application, considering factors like accuracy, speed, and economic efficiency, showing that it could be effectively implemented in chili sorting machines. However, further refinement is needed to improve accuracy in certain environmental conditions. Additionally, the research provides insights for the further development and application of image detection technology for sorting other agricultural products, aiming to increase efficiency and reduce waste in agricultural production processes.

Risk analysis of developing vision problems for learners using data mining techniques

Tanasiri Benjaarepron — 2024-09-16

This research investigates vision problems among higher education students, with the primary objective of exploring their eye usage behaviors and identifying risk factors contributing to conditions such as myopia, hyperopia, and astigmatism. Data were collected from 100 students through in-depth questionnaires. Data Mining techniques were used to examine the relationship between eye usage behaviors and the occurrence of vision problems. The results indicated that 35% of the students had myopia and astigmatism, while 17% reported no vision problems. Among the models used - Decision Tree, Naïve Bayes, Lazy IBK, and Multilayer Perceptron – the Multilayer Perceptron model had the highest accuracy at 99%. The research also offers recommendations for improving eye usage behaviors and implementing appropriate eye rest practices to reduce the long-term risk of vision problems.

Development of reed diffuser product Inhalation on Emotional States, Autonomic Nervous System

Saengsit Kritsadee — 2024-09-18

This research was to study the support of the automatic control system for the inhalation of fragrant reeds by quasi-experimental research measuring before and after 32 healthy volunteers inhaled the scent of almond oil and fragrant reeds. Herbs record the results of vital signs. While resting while inhaling almond oil. and while inhaling the scent of the stalks Compare using Matched t-test statistics. The results of the study found that while resting while inhaling almonds while inhaling the wood core odor. systolic means were 115.77, 115.28 and 120.05 mmHg, respectively; After that they were compared. The values between inhaling the wood stem and while inhaling the almond aroma were found to be significantly different at the 0.05 level (P-value = 0.005). diastolic means were 74.43, 74.27 and 77.98. mmHg, respectively; when comparing the values while inhaling the aroma of the wood stalks and while inhaling the aroma of almonds, it was found to be significantly different. Statistically significant at the 0.05 level (P-value = 0.027), heart rate means were 81.97, 81.73, and 83.26 beats/min., respectively, compared with the values between inhaling the scent of herbal reeds and inhaling the scent of almond oil. Found a statistical difference at the level of 0.05 (P-value = 0.016). It was found that while resting, inhaling the scent of fragrant reeds. Detects toxins and senses the taste of the body in the movement of the clearing, sensual mind, the essence of the still spoiler mind. High efficiency after smelling almonds and has a statistical level of 0.05 (P-value = 0.000) without irritation from the herb causing automatic changes. Reduced periods of movement and changes in emotions and feelings.

Skeuomorphism and Flat Design: UX/UI Design Aligned with Human Perception Processes.

Mathayom Onchan — 2024-10-08

This research aims to: 1) study the principles of Human-Computer Interaction (HCI) and the concepts of two interface design styles-Skeuomorphism and Flat Design, and 2) design a UI/UX prototype application for customer order-taking in restaurants, focusing on user needs and enhancing operational efficiency. Research Tools: This study uses questionnaires to explore user behaviors and requirements, observations of the prototype application usage, and interviews with restaurant order-taking staff to gather data on ease of use, aesthetics, and real-world application responsiveness. Population: The study population consists of 10 order-taking staff from an Isan restaurant. They were observed and interviewed to assess their satisfaction, ease of use, and the suitability of the prototype application. Statistical Analysis: Basic statistics such as mean and standard deviation were used to evaluate the results. Research Findings: Section 1: General Information of Respondents Number of respondents: 10 Gender: Mean = 1.50, Standard Deviation = 0.52705 (50% male) Age: Mean = 1, Standard Deviation = 0.00 (100%, mostly part-time students) Section 2: Satisfaction with Application Use 2.1 Quality of Application Ease of use: Mean = 4.70, Standard Deviation = 0.48 Convenience: Mean = 4.70, Standard Deviation = 0.48 Accuracy: Mean = 4.80, Standard Deviation = 0.42 Speed: Mean = 5.00, Standard Deviation = 0.00 2.2 Application Security Reliability of notification system: Mean = 4.70, Standard Deviation = 0.48 Individual login system: Mean = 5.00, Standard Deviation = 0.00 Accuracy of data processing: Mean = 5.00, Standard Deviation = 0.00 2.3 Application Presentation Text appropriateness: Mean = 5.00, Standard Deviation = 0.00 Component placement: Mean = 4.60, Standard Deviation = 0.51 Use of symbols and media: Mean = 4.30, Standard Deviation = 0.48 Aesthetics: Mean = 4.80, Standard Deviation = 0.42 Modernity: Mean = 4.40, Standard Deviation = 0.51 The use of skeuomorphism in mobile UX design and making interfaces more familiar and user-friendly originated from the early days of computers and mobile devices. Flat Design, on the other hand, emphasizes simplicity by reducing unnecessary details and focusing on bright colors, flat icons, and clean shapes. This design approach aims to enhance usability. When these two styles are combined in design, they can result in a well-designed and fast application. Research indicates that applications designed in the Flat Design style are rated higher in terms of clarity and ease of use compared to the Skeuomorphism style. As a result, Flat Design can be further developed to create efficient applications that better meet user needs in real-world contexts.

Creating an Accessible Community Database System of Traditional Healers in Sakon Nakhon Province.

Wuttipong Hamvong — 2024-10-08

The research focuses on development of an accessible database system for traditional healers in Sakon Nakhon Province. The objectives were to survey, collect, and disseminate information on traditional healers using this database system. The study covers 18 districts and 125 sub-districts in Sakon Nakhon Province. The database was, developed with PHP and Thunkable, and is managed with Microsoft Access and MySQL to ensure an efficient relational database. The survey results identified a total of 1,545 traditional healers, with 1,422 registered with the Provincial Public Health Office. The majority of the healers are male (54.07%) and are aged between 61-70 years (37.34%). The primary motivation for becoming a traditional healer is the inheritance of knowledge from ancestors (42.2%), with most specializing in herbal compress massage (30.75%). The system’s effectiveness was evaluated by five computer experts, who gave it an average score of 3.81 (SD = 0.16), indicating a good level. User satisfaction was assessed among 412 users, with an average score of 3.60 (SD = 0.77), indicating a high level of satisfaction. This research provides an effective and widely accepted database system that will help preserve and disseminate traditional medical knowledge in Sakon Nakhon Province, benefiting the community and the broader public health sector.