TY - JOUR AU - เอกโยธินวงศ์, กรกนก AU - ศากยวงศ์, นิรมล AU - ดำริห์อนันต์, สมจิต AU - นาคบรรพต, วรนันต์ PY - 2019/12/16 Y2 - 2024/03/29 TI - ฤทธิ์ต้านอนุมูลอิสระและสารออกฤทธิ์ทางชีวภาพของสารสกัดกะเม็ง JF - Thai Journal of Science and Technology JA - Thai J. Sci. Technol. VL - 9 IS - 1 SE - วิทยาศาสตร์ชีวภาพ DO - 10.14456/tjst.2020.5 UR - https://li01.tci-thaijo.org/index.php/tjst/article/view/229697 SP - 45-57 AB - <p>The extracts of medicinal Thai herb Kameng (<em>Eclipta prostrata</em> Linn.) were subjected to study antioxidant activity and bioactive compounds. The maceration extractions of the branches, leaves, and flowers of Kameng plants by distilled water, 30 % (v/v) ethanol, 70 % (v/v) ethanol, 99 % (v/v) ethanol, and ethyl acetate, were performed. The crude 30 % (v/v) ethanol extracts showed more total polyphenol contents (TPC) (168.8±47.7, 227.8±34.9 and 198.1±13.2 mg GAE/g crude extract from branches, leaves and flowers, respectively), total flavonoid contents (TFC) (38.1±11.9, 56.4±14.8 and 45.0±11.5 mg EPE/g crude extract in branches, leaves and flowers, respectively), and antioxidant activity by DPPH method (0.61±0.2, 0.63±0.2 and 0.65±0.3 mg/mL of IC<sub>50</sub> values for the extracts from branches, leaves and flowers extracts, respectively), compared to those of other solvents. Bioactive compounds in the extracts were analyzed by thin layer chromatography (TLC) and high performance liquid chromatography (HPLC), and major compounds i.e. gallic acid, chlorogenic acid, caffeic acid, vanillin, p-cumalic, rutin, narigenin, myricetin, epicatechin and wedelolactone were reported.</p> ER -