The Prevalence of Hyperuricemia and Associated Factors in the Rural Community, Khon Kaen Province.

Abstract

Background and objective : Hyperuricemia is not only related to gout and renal stones but also various kinds of chronic diseases.  This study aimed to investigate the prevalence of hyperuricemia and its association with various factors in rural residents of Khon Kaen.

Methods: A cross-sectional study in 16   villages from 4 districts of Khon Kaen was  conducted. Studied population were randomly selected by multistage sampling.

Results : The study included 2,128 subjects aged 15 to 65 years, 36.4 % were male, 47.5% were between 46-60 year old and 75.8% were farmers. The prevalence of hyperuricemia with age and sex adjustment was 11.8% (95%CI: 10.4, 13.2), in males (>7.0 mg/dl) 14.9% and in females (>5.7 mg/dl) 8.6%. By multiple logistic regression hyperuricemia was significantly associated with sex(male), obesity and purine rich food aggravation. The adjusted odds ratios and 95%CI  were 1.5 (1.1,2.0), 1.6 (1.2,2.1) and 1.4(1.1,1.9), respectively.     

Conclusions: One in 8-9 rural dwellers in Khon Kaen had hyperuricemia which is comparable to the results of other studies in other parts of Thailand. In this region purine rich food aggravation (bamboo shoots,meat,insects) is remarkably one of the three associated factors out of male and obesity.

 Key words: purine rich food aggravation, hyperuricemia, obesity, rural area