MALE BREAST CANCER : The first case of a Pathological Report in Srinagarind Hospital

Abstract

Background and objective : Breast cancer is an uncommon disease in men. The review of the pathological reports in Srinagarind Hospital, KKU from 1975 to 2009 showed only one case that was diagnosed as male breast cancer. The clinical features, morphology and immunohistochemistry study of this case are presented here.

Methods : Reviewed the clinical history from OPD card and  studied histopathology and immunohistochemistry by microscopy.

Results : The patient first symptom presented itself as a palpable breast mass (2.5 cm in diameter), located at the lower inner quadrant of right breast. The microscopic finding was invasive ductal carcinoma grade II. The immunohistochemistry study showed positive for Estrogen receptor (3+).

Conclusion :  Invasive ductal carcinoma is rare in males. Their histopathological pattern was remarkably similar to those seen in female breast cancer but showed a stronger expression of estrogen receptors than those detected  in females.

Keywords : male breast cancer, invasive ductal carcinoma, estrogen receptor.