Prostate cancer in Srinagarind Hospital

Abstract

Background and Objective: Prostate cancer is the second common cancer in elderly male in worldwide, especially Western countries. In contrast, its incidence is low in Asia. However, the incidence rate is now being diagnosed with yearly increasing frequency due to increasing proportion of elderly person. In Thailand, the prostate cancer with general data and histopathologic features has not been completely described. Therefore, the aim of this study was to analyze the history records of patients who were diagnosed with prostate cancer in order to provide the information for the efficient prostate cancer diagnosis and treatment.

Methods: This retrospective descriptive study was performed on the review of medical records of patients who were diagnosed prostate cancer between January 1, 1985 to December 31, 2010 at Srinagarind Hospital, Faculty of Medicine, Khon Kaen University. Information was included age, PSA levels, surgical procedures, histological reports, and radiological reports. These data were analyzed for descriptive statistics.

Results: There were 406 patients diagnosed with prostate cancer, mean age 69.24 (29-91) years and mean serum PSA level (2.43 to ≥ 100) ng/ml. The patients group with Gleason score 5-7 were the most of the pathological report, 145 (33.64%) followed by 120 (27.84%) patients with Gleason score 8-10, 59 (13.69%) patients with Gleason score 2-4, respectively. Multiple bones metastasis was detected in 173 (42%) patients. Hip bone was the most common site for metastasis, 140 (80.92%) patients.

Conclusion: The most patients with prostate cancer are diagnosed above 50 years old and the average of serum PSA levels was highly (59.99 ng/ml). In addition, hip bone was the most common metastasis.