Iodine – Induced Thyroid Disease
Abstract
When the diet of humans is greatly deficient in iodine , goiter almost in variably ensues, sometimes accompanied by hypothyroidism. More surprising is that exposure to excess iodine sometimes leads to the development of thyroid disease. These abnormal responses are based on the intrathyroid pathways of iodine metabolism . The manifestations may be iodine-induced hypothyroidism and hyperthyroidism. These disorders are not rare and should be considered because many forms of diet and medications are iodine-containing compounds.