Experimental Studies on the Use of K1 K8 Raw Thai Silk in Skin Wound Suture
Abstract
Abstract
The raw silk of 120 – 240 deniers from K1 K8 silk worms reared in Khon Kane was used as a suturing material for the middorsal and midventral surgical wounds of the rats. The identically – made skin wounds of the control group were sutured by Mersilk W775, Ethicon. Both groups of animals were kept pathogen free in the 12 : 12 hr. dark and light room and maintained on a standard rodent diet at Charring Cross and Westminster Mjedical School. The experimental animals were kept 7 days (middorsal wounds) and 10 days for the group simulated the laparotomy wounds. We observed the animals after operation rery closely. The wound tissues were processed through the histopathological techniques for microscopic study. We found that skin wounds sutured with K1 K8 Thai silk gealed in a similar manner to those treated with commercially available silk suture (Mersilk) but the former presented difficulties in manipulation on the tissue background during operation. The rough texture of the raw silk did not facilitate as neat a suture as the commercial silk. In conclusion we gave seen no adverse reaction but regeneration was achieved. The tensile strength and the durability of the K1 K8 raw Thai silk Should be further investigated.