COMPATIVE ERYTHROPIETIN LEVELSINURINE OF THE ANEMIC AND MALNOURISHED PATIENTS
Abstract
The 24 – hour urinary excretion of erythropoietin was biologically assayed in the 33 anemic patients and the 8 patients with protein – energy malnutrition from Chiang Mai Hospital, Chiang Mai university, Thailand. The erythropoietic activity in the patients’ urine was measured by radiobiological technique in starved rats, comparing with that of the 18 healthy subjects living in the same area. This investigation indicates that the urinary erythropoietin level in patients with all types of animas is approximately 62 per cent higher than in the malnourished patients. The average urinary erythropoietic activity of anemic patients is 297 .11 ± 46.95 Co Units per 24 – hour Urine, While that of the patients with protein – energy malnutrition is only 187 .66 ± 16.15 Co Units per 24 – hour Urine. In the case of anemic patients, the urinary erythropoietin level in patients, the urinary erythropietin level in aplastic anemia is the highest among the group, in which the average activity is equal to 725.94 ± 88.31 Co Units per 24 hour Urine.