Study of Enzyme Cholinesterase Levels of Farmers in Kud – Kwang village
Abstract
ABSTRACT
The enzyme cholinesterase level of 64 farmers in Kud – Kwang village of Nong – Rue Disrict, Khon Kaen province were investigated. Following general health examination, blood samples were drawn from the farmers exposed to anticholinesterase insecticide. The specimens were collected in two periods : 1) during the period of intensive and frequent utilization of insecticides in the farm, and 2) during the time without any insecticidal uses. The two collecting periods were six months apart. The results of blood analysis from both both collections were interpreted together. Of the 26 volunteer farmers investigated, cholinesterase was found to be inhibited in 15 volunteers, whereas the enzyme was not inhibited in 9 of them. However, the result from the other two fafmers was uninterpretable.
The insecticides commonly used were organonitrogen and organophosphate. The common symptoms indicationg intoxication were dry throat, hadche, dizziness, and general weekness. The volunteer farmers took medication (for prevention and treatment) both before and after insecticide that 21 farmers took medication (for prevention and treatment) both before and after insecticide uses, while 5 of them did not. The studies also reveated that 15 farmers had prophylactic medication, whereas the rest took the medication only when intoxicated.
Key words
Cholinesterase human insecticide intoxication organonitrogen organophosphate