The in vitro activity of OPC-17116, a new 5-methyl substituted quinoloneagainst Burkholderia (Pseudomonas) pseudomallei

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Wanlop Kaewkes
Vajarabhongsa Bhudhisawasdi
Surasakdi Wongratanacheewin

Abstract

Abstract

Fifty clinical isolates of Burkholderia(Pseudomonal) pseudomallei were tested by broth microdilution technique for susceptibility to OPC-17116 , a new 5-methyl substituted quinolone. The minimul inhibitory concentration (MIC) range was 1-8 µg/ml. The MIC 50 and MIC 90 were 2.6 µg/ml and 0.4 µg/ml, respectively.

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1.
Kaewkes W, Bhudhisawasdi V, Wongratanacheewin S. The in vitro activity of OPC-17116, a new 5-methyl substituted quinoloneagainst Burkholderia (Pseudomonas) pseudomallei. Srinagarind Med J [nternet]. 1 [cited 2021Nov.29];9(3):100-2. vailable from: https://li01.tci-thaijo.org/index.php/SRIMEDJ/article/view/13752
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Original Articles