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Fifty clinical isolates of Burkholderia(Pseudomonal) pseudomallei were tested by broth microdilution technique for susceptibility to OPC-17116 , a new 5-methyl substituted quinolone. The minimul inhibitory concentration (MIC) range was 1-8 µg/ml. The MIC 50 and MIC 90 were 2.6 µg/ml and 0.4 µg/ml, respectively.
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