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Background: Severe pre-eclampsia is not an uncommon obstetric complication. The incidence or risk factors for this complication in Srinagarind Hospital has not previously been studied.
Objectives : 1. To analysel the ratio of severe pre-eclampsia to total number of deliveries in Sringarind hosptialj ; 2. The risk factors for severe pre-eclampsia; and 3. The modes of delivery and the condition of the infant born to mothers with severe pre-eclampsia.
Design: A descriptive case-controlled study.
Setting: Department of Obstetrics and Gynecology, Srinagarind hosptial. Faculty of Medicine, Khon Kaen University, Thailand.
Subjects: 10, 580 women who has delivered at Srinagarind Hospital between January 1, 1992 and December 31, 1993.
Main outcome measures: Ratio of cases of Sever pre-eclampsia to total number of deliveries, and risk factors analysed by multiple logistic regression.
Results: The incidence of severe pre-eclampsia was 0.96 per 100 deliveries. Thei risk factors were primigravida status (adjusted OR:2.4,95%CI: 1.3-4.3); base history of pre-eclampsia (adjusted OR:0,95%CI: 2.7-18.8); gestational diabetes (adjusted OR:4.6,95%CI: 1.3-16.6); and body mass index of more than 20 kg/m2 prior to the pregancy (adjusted OR:3.3,05%CI: 1.3-8.2). The most common mode of delivery was cesarean section, while normal vaginal birth was the most common mode of delivery in the case and control groups were 2599.7 grams (SD. = 699.4) and 3095.7 grams (SD. = 420.7), respectively. The percentrage of infacnts with a low birth weight (less than 2500 grams) in the pre-eclampsia group was 40.6% compared with 5.9% in the control group. Severe birth asphyxia occurred in 9.9 % of the pre-eclampsia group compared with 1.8% in the control group.
Conclusion: Severe pre-eclampsia is not uncommon in Srinagarind Hospital. It was found in 0.96 per 100 deliveries. The risk factors are primigravida status, past history of pre-eclampsia, grestational diabetes, and body mass index of more than 30 kg.m2 prior to the pregnancy. Themost common mode of delivery was the most common in the controls group. The gestational age, birth weight and apgar score of infants in the pre-eclampsia than the control group.