Tyes of Spontaneous Passing Stones in Rural Community, Khon Kaen,Thailand.

Abstract

Background and objective  :  The types of the nephrolithiasis is very important for the selection of the types of investigation treatment and prevention. Reports from many countries revealed the different types of the nephrolithiasis from surgical remove and the spontaneous passed stones. In Thailand, there are some reports about types of the stones from surgical interventions, but no report for the types of spontaneous passing stones. This study aimed to investigate the types of spontaneous passed stones in rural area of  Khon  Kaen, Thailand.

Methods:  This is  an exploratory study. The collection of the spontaneous stones made  by announcing the stone patients who passed the stone to bring the stones to the mobile ultrasound team and filled the self administered questionnaire. The study was performed during December 2007-March 2009. The announcements were done by the village health volunteers/ the village leaders in Nam Phong and Muang district, Khon Kaen Province. The stone were analyzed using the biochemistry department, faculty of medicine using the infrared spectrophotometry.

Results: The total of 84 passed stones were collected. The result of the analysis were uric acid stone, calcium oxalate/phosphate, calcium oxalate and calcium phosphate  41.7, 29.7, 27.4 and 1.2 percent, respectively. There were 43.7 percent of these patients reported the 2-3 times of spontaneous passing of stones  within the past 5 years. This study found the significant association between uric stone type and the symptoms aggravated by purine rich foods (Odds ratio (95% CI): 3.88 (1.35,11.37). There was no significant association between stone types and age and sex of the patients.

Conclusions:  By infrared spectrophotometry, 41.70 percent of the spontaneous passed stones were uric acid, compare to 3 percent  in  the larged surgically removed stones previously reported as uric acid.