Prevention of Chemotherapy-induced Nausea and Vomiting

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Suthan Chanthawong


"Chemotherapy-induced nausea and vomiting (CINV) is a common adverse event. It affects the quality of life of cancerous patients and may lead to other complications. CINV can cause non-compliance issues in cancer treatment. Several international organizations initiated recommendations for the prophylaxis of CINV. Nonetheless, a real clinical practice setting, CINV could not be completely preventable. This has led to the development of CINV prophylactic regimens, including the development of quadruplet regimen and addition of new antiemetic drugs to previous standards. The clinical studies of non-pharmacological therapy for CINV prevention are still in need to support the effectiveness and safety to ensure the confidence of the health care providers for the application in clinical practice."

Keywords: Chemotherapy-induced nausea and vomiting, corticosteroids, 5-HT3 receptor antagonists, NK-1 receptor antagonist, olanzapine.


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