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Background and Objective: Colorectal carcinoma is the most common malignancy of the gastrointestinal tract. It is the third common cancer in men, the fourth common cancer in women, and the fifth common cancer for both sex in the world1. When patients come to the hospital with gastrointestinal symptoms ,frequently it is too late. Early detection along with improvements in medical and surgical care are thought to be responsible for the decreasing mortality of colorectal cancer observed in recent year. The best way to find early cancer of colon , potential people were selected for screening colonoscopy2.
Materials and methods: The potential people(50-70 years old and positive Fit-test)and no contraindication for colonoscopy 822 cases were selected and performed screening colonoscopy from December 2017 – January 2019 in Kasetwisai Hospital.
Results: There were well differentiated adenocarcinoma in 11 cases ( 2.09 %) and all were stage II by TNM Staging whom received medical and surgical care. Adenomatous polyp and tubulovillous adenoma were found in 169 cases ( 21.16 % ) were diagnosed and performed polypectomy.In this group there were intermediate and high risk polyps (large polyp/tubulovillous adenoma) 45 cases (4.43% ) . Others were diverticulums 61 cases (8.06%) ,colitis/proctitis 30 cases (4.42%) , parasitic infestation 12 cases (1.16%) and hemorrhoids 3 cases (0.7%) . The complication was colonic perforation in 2 cases (0.24%).
Conclusion: It is now well accepted that the majority of colorectal carcinoma was evolved from adenomatous polyp; the sequence of events is adenoma – carcinoma sequence.The incidence of invasive carcinomas increase with size (35-50% in polyp larger than 2 cm )3. This study could eliminated colorectal cancer strategies by targeting the neoplastic polyps for removal before malignancy develops in 169 cases (21.16 % of all the potential people 822 cases).
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