Accuracy of Magnetic Resonance Imaging in Diagnosis of Morbidly Adherent Placenta
Keywords:
morbidly adherent placenta; placenta accreta; placenta increta; placenta percreta; pelvic MRIAbstract
Background and Objective: To determine the sensitivity and specificity of MRI findings for detecting of morbidly adherent placenta.
Methods: A retrospective review of the patients who underwent pelvic MRI during pregnancy between January 2004 and June 2014. Thirty-one image sets that met the following inclusion criteria were enrolled in the study. MR imaging findings included uterine bulging, intraplacental hemorrhage, placenta heterogeneity, intraplacental dark bands, present of myometrium plane were reviewed by two investigators blinded to pregnancy outcome.
Results: In thirty-one image sets of pelvic MRI in the pregnant patients. Sensitivity, specificity, PPV, NPV and kappa value of MRI features had calculated: uterine bulging (90.9%, 75%, 66.7%, 93.8% and 0.74 respectively); intraplacental hemorrhage (81.8%, 89.5%, 81.8%, 89.5% and 0.78); placental heterogeneity (100%, 15%, 39.3%, 100% and 0.34); intraplacental dark bands (100%, 55%, 55%, 100% and 0.49); partial/absent myometrium under placenta (100%, 80%, 73.3%, 100% and 0.83), respectively.Accuracy of MRI to diagnosed morbidly adherent placenta was 83.8% (95% CI 66.2%-94.5%) with moderate interobserver agreement (kappa value 0.58).
Conclusion: Uterine bulging, intraplacental hemorrhage and partial/absent myometrium plane may be the keys criteria to diagnosis on pelvic MRI. Placental homogeneity and absent intraplacental dark band on T2WI may be exclusive criteria.
References
2. WuS. Abnormal placentation: twenty-year analysis. Am J of Obstet Gynecol 2005; 192: 1458-61.
3. Center for Disease Control and Prevention. Births: Final data for 2012. National Vital Statistics Reports 2013; 62: 1-67.
4. Lim PS, Greenberg M, Edelson MI, Bell KA, Edmonds PR, Mackey AM. Utility of Ultrasound and MRI in Prenatal Diagnosis of Placenta Accreta: A Pilot Study. Am J Roentgenol 2011; 197: 1506-1513.
5. Derman AY, Nikac V, Haberman S, Habeman S, Zelenko N, Opsha O, et al. MRI of placenta accreta: A new imaging perspective. Am J Roentgenol 2011; 197: 1514-1521.
6. Kim JA, Narra VR. Magnetic resonance imaging with true fast imaging with steady-state precession and half-Fourier acquisition single-shot turbo spin-echo sequences in cases of suspected placenta accreta. Acta Radiol 2004; 45: 692–698.
7. Lax A, Prince MR, Mennitt KW, Schwebach JR, Budorick NE. The value of specific MRI features in the evaluation of suspected placental invasion. MagnReson Imaging 2007; 25: 87–93.
8. Maldjian C, Adam R, Pelosi M 3rd, Rudelli RD, Maldjian J. MRI appearance of placenta percreta and placenta accreta. Magn Reson Imaging 1999; 17: 965-971.
9. Viera AJ, Garrett JM. Understanding interobserver agreement: The Kappa statistic. Fam Med 2005; 37: 360-363.
10. Cali G, Giambanco L, Puccio G, Forlani F. Morbidity adherent placenta: Evaluation of ultrasound diagnostic and differentiation of placenta accreta from percreta. Ultrasound Obstet Gynecol 2013; 41: 406-412.
11. WarshakCR, Eskander R, Hull AD, Scioscia AL, Mattrey RF, Benirschke K, et al. Accuracy of ultrasonography and magnetic resonance imaging in the diagnosis of placenta accreta. Obstet Gynecol 2006; 108 (3 Pt 1): 573-581.
12. DwyerBK, Belogolovkin V, Tran L, Rao A, Carroll I, Barth R, et al. Prenatal diagnosis of placenta accreta: sonography or Magnetic resonance imaging? J Ultrasound Med 2008; 27: 1275-1781.
13. Varghese B, Singh N, George RA, Gilvaz S. Magnetic resonance imaging of placenta accreta. Indian J Radiol Imaging 2013; 23: 379-385.