Complications of Advanced Maternal Age Pregnancy: A Retrospective Cohort Study
Keywords:
advanced maternal age, complication, retrospective cohort study.Abstract
Objective: To study the percentage of advanced maternal age pregnancy (>35 years) and the pregnancy complications when compare with 20-34 years old group.
Materials and Methods: A retrospective cohort study in the women who delivered in Phen and UdonThani Hospitals during January 2019 to August 2021. The medical records were retrospectively reviewed, then the descriptive statistics, univariate and multiple logistic regression analysis were performed.
Results: The advanced maternal age pregnancy were 1,719 cases/ 9,330 total deliveries (18.42%). In this group, 57.01% had one or more complications. The most common were preterm delivery (15.30%) and gestational diabetes (13.03%). The risk of gestational diabetes, preeclampsia, and fetal macrosomia were increased in the advanced maternal age group when compared with 20-34 years old group with the adjusted Odds ratio 2.91 (95%CI 2.35-3.58), 1.33 (95%CI 1.08-1.64) and 1.51 (95% CI 1.08-2.10), respectively.
Conclusion: The prevalence of advanced maternal age was 18.42% of total deliveries. The risk of gestational diabetes, preeclampsia, and fetal macrosomia were increased in this group. Therefore, these complications should be aware in this maternal age group.
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