Incidence and Quality of Life of Early Childhood with Thyroid stimulating hormone greater than 25 mU/L in Sakon Nakhon Hospital

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Somnuk Apiwantanagul
Sudarat Sirichaipornsak
Niyada Boonapai


Background and Objective:  Infants with Thyroid-stimulating hormone greater than 25 mU/L (TSH > 25 mU/L) are more likely to have developmentally delayed, cognitive and motor impairment, affecting the quality of life of children.  This study aimed to determine the incidence of newborns with congenital hypothyroidism, and quality of life in early childhood with TSH > 25 mU/L.

Methods: This descriptive study was conducted on 27 early childhood who had TSH levels greater than 25 mU/L, and their caregivers from 2016 to 2020 in Mueang district, Sakon Nakhon province. Data was collected at well-baby clinics by questionnaires. The index of item objective congruence was at .89 and Cronbach’s alpha coefficient was 0.85. The data was analyzed using descriptive statistics.

Result: The incidence of newborns with congenital hypothyroidism was 1:1,116. The overall quality of life in early childhood with TSH > 25 mU/L was poor at 75.6%. The lowest score was the social relationship and physical health 67.6%, and 72.7%, respectively. Most of them have a poor level of health and wellness at 79.6%.
: Incidence of congenital hypothyroidism in Sakon Nakhon hospital still high, and most early childhood had poor quality of life. There is a need for all pregnant women to take an iodine supplement every day, and take care of the growth, and stimuli of the newborn to improve social, physical, and quality of life.


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Apiwantanagul S, Sirichaipornsak S, Boonapai N. Incidence and Quality of Life of Early Childhood with Thyroid stimulating hormone greater than 25 mU/L in Sakon Nakhon Hospital. SRIMEDJ [Internet]. 2022 Jun. 24 [cited 2022 Oct. 5];37(3):212-7. Available from:
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