Factors Associated with Mortality in Patients with Coronavirus 2019 (COVID-19) Infection at Roi Et Hospital
Keywords:
Coronavirus 2019, death, patient infected with COVID-19Abstract
Background and Objective: The coronavirus disease 2019 (COVID-19) is an emerging disease that spreading around the world. Some of the infected patients had severe symptoms and resulted in death. The objective of this study was to investigate the factors associated with mortality of patients with COVID-19 infection admitted at Roi Et hospital.
Methods: The study design was a hospital based case-control study. The study subjects were patients with COVID-19 infection that was confirmed by RT-PCR and admitted at Roi Et Hospital between January 1, 2020 to May 31, 2022. The case group was 95 patients with COVID-19 infection and deaths. The control group was 95 patients with COVID-19 infection but no deaths. Data were collected from medical records. The statistical analyses used descriptive statistics, Chi-square test, univariate analysis, and multiple logistics regression. The statistical significance was set at a p-value < 0.05.
Results: Of 95 patients of case group, most of them were female 53.68%, mean age of 63.82 years (SD=17.97). In 95 cases of control group, most of them were male 67.37%, mean age of 62.95 years (SD=13.25). The logistic regression analysis revealed factors associated with in-hospital mortality of COVID-19 patients were male (Adj.OR.=2.56; 95%CI: 1.36-4.82), age 71-80 years (Adj.OR.=2.66; 95%CI: 1.16-3.67), age > 80 years (Adj.OR.=2.48; 95%CI:1.18-4.92), Body mass index >30 (kg/m2) (Adj.OR.= 2.70; 95%CI:1.22-2.15) , comorbidity (Adj.OR.=1.95; 95%CI:1.14-3.22), sepsis (Adj.OR.=1.94; 95%CI:1.09-4.21), lung infiltration on both sides (Adj.OR.=2.49; 95%CI:1.65-3.38), underwent with mechanical ventilator (Adj.OR.=2.49; 95%CI:1.91-35.8), and unvaccinated patients. (Adj.OR=1.98; 95%CI: 1.01-3.68).
Conclusion: This study found that factors associated with mortality of patients infected with COVID-19 admitted at Roi Et hospital were male, elderly, obesity, comorbidity sepsis, lung infiltration on both sides, mechanical ventilation used, and unvaccinated patients.
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