Effectiveness of Red Yeast Rice Extract for Blood Lipid Lowering Effect in Hyperlipidemic Individuals
Keywords:
red yeast rice extract, hyperlipidemia, cholesterol, low-density lipoprotein (LDL) cholesterol, triglyceridesAbstract
Background and Objective: Dyslipidemia is a risk factor for ischemic heart disease, the leading cause of death. Red yeast rice consists of substances that decrease blood lipid levels. The purpose of this study was to investigate the effectiveness of consuming red yeast rice extract in decreasing low-density lipoprotein (LDL) cholesterol and cholesterol.
Method: The experimental study was performed at the Medical Correctional Hospital. The population included 20 medical staffs, aged 35-60 years, and was randomly divided into two groups of 10 people each. The experimental group received red yeast rice extract (500 mg/day), while the control group received a placebo. The study period was 8 weeks, and data was analyzed using a student t-test and repeat analysis of variance (ANOVA) tests.
Result: The average cholesterol level in the experimental group at 8 weeks after starting the project decreased by 30.80±6.10 mg/dl, which was statistically significant (p=0.038), while the levels of low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, and triglycerides were not different. However, triglyceride levels increased on average 44.30±3.18 mg/dl in the control group at 8 weeks after starting the project, which was statistically significant (p=0.044). Other laboratory results were not different at before and after the experiment began.
Conclusion: Red yeast rice extract could reduce blood cholesterol levels.
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