Proportion of Workers Exposed to Heat Stress Having Rising Urine Neutrophil Gela Tinase Associated Protein Level in a Steel Manufacturing Factory in Khon Kaen Province
Keywords:
Acute Kidney Injury (AKI), NGAL (neutrophil gelatinase-associated protein), Employees, HeatAbstract
Background and objective: Chronic kidney disease occurs globally and is related to increasing age. One of the causes of kidney disease in working age is exposure to heat in the workplace. Metal smelting factories are one area where high temperatures are common. Employees have to work close to the melting furnaces. This study aims to find the proportion of employees with rising of neutrophil gelatinase-associated protein; NGAL in urine, which can predict acute kidney injury in one steel production factory.
Methods: A cross-sectional descriptive study was conducted. All 93 workers whom exposed to heat in steel factory were recruited as a study population. Collected data from whole study population. Wet bulb globe temperature; WBGT was measured. Dehydration was determined as urine specific gravity via urine strip. NGAL was measured by enzyme-linked immunosorbent assay; ELISA technique to determine early acute kidney injury. Data were collected in November 2019.
Results: Workers experienced dehydration on the first day and the last day of working, with percentages of 27.7% and 35.4%, respectively. The proportion of employees with increased NGAL levels between the first and last days of working were 40.0% and 46.6%, respectively. No workers suffered with kidney impairment due to working exposed to heat were found.
Conclusions: Dehydration and an increase in NGAL levels after work may indicate that these workers are at risk of developing acute kidney injury. Although no worker was found kidney impairment due to working in heat.
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