Hepatocellular Carcinoma in Srinagarind Hospital: a 5-Year of Experience

Abstract

Background and Objectives: Hepatocellular cancer (HCC) is an aggressive cancer frequently occurring in Asia countries, including Thailand. The aim of this study is to review the trends and characteristics of HCC patients, who received treatment in Srinagarind hospital, survival time of patients with different stages of disease and treatment modalities studied during 2008-2012.

Methods: All new HCC cases registered in Srinagarind hospital between January 1^st, 2008 and December 31^st, 2012 were included in this study. Our data were obtained from the Khon Kaen Cancer Registry. The characteristics of patients and survival time were analysed.

Results: There are 2,202 total HCC patients enrolled in this study. HCC was presented in male with higher frequency compared to female almost 4 folds (3.59: 1). A trend of both male and female HCC patients studied during 2008-2012 was rising. The majority of HCC patients commonly presented with stage 4 of disease (42.72%). Overall median survival time of all HCC patients was 4.6 months (95% confidence interval (CI), 4.17, 5.2). The overall median survival time for stage I, II, III and IV were 18.5, 16.4, 6, and 3.1 months, respectively.

Conclusion: The trends of HCC are increased to accelerating rate. If HCC can be recognised at the early stage of disease resulting in early diagnosis, this will have a significant impact on the survival time and prognosis of HCC patients.