Mechanisms of Penile Erection, Erectile Dysfunction and Treatment

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Kutcharin Phunikhom
Kovit Khampitak
Chantana Aromdee
Tarinee Arkaravichien
Jintana Sattayasai


Erectile dysfunction (ED) is a common problem in general populations. Although ED is not life threatening, it is distressing to the sufferers and their partners, and puts a strain on their relationships. The etiology of ED is believed to be multifactorials; both organic and psychological problems. Physicians have to investigate for the etiology and co-morbidity of ED. The treatment is composed of both non-pharmacological and pharmacological therapies. The first line treatment drug is phosphodiesterase inhibitor (PDE-5 inhibitors). However, other therapies have not yet been approved by the Food and Drug Administration regarding the therapeutic efficacy and safety. In addition, there are many researchers around the world are studying for novel therapies; these may be achieved in the near future


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Phunikhom K, Khampitak K, Aromdee C, Arkaravichien T, Sattayasai J. Mechanisms of Penile Erection, Erectile Dysfunction and Treatment. SRIMEDJ [Internet]. 2016 Apr. 29 [cited 2023 Nov. 29];31(2):228-39. Available from:
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