• Kittipak Jenghua School of Pharmaceutical Sciences, University of Phayao, Phayao
  • Harisadee Sangtong School of Pharmaceutical Sciences, University of Phayao, Phayao
  • Narissara Jaiya School of Pharmaceutical Sciences, University of Phayao, Phayao
  • Warinat Jaroenteerawit School of Pharmaceutical Sciences, University of Phayao, Phayao
  • Apisara Khiewpradang School of Pharmaceutical Sciences, University of Phayao, Phayao



elderly, potentially inappropriate medications, Thailand criteria, prevalence, factors associated


The Lists of Risk Drugs for Thai Elderly (LRDTE) was recently developed. No studies reported the prevalence of potentially inappropriate medications (PIMs) use among the urban community-residing elderly using the LRDTE as an assessment tool. The purposes of the study were to determine prevalence, inappropriate medicine items, and factors associated with PIMs use. This research involved a cross-sectional analytic survey by collecting data on medication use of people aged ³ 60 years living in seven urban communities, Phayao province between August 15, 2016 and February 24, 2017. PIMs were identified using the Lists of Risk Drugs for Thai Elderly (LRDTE). Of four hundred elderly persons, they were mostly female (67.3%) with an average age of 72.26 ± 8.73 years. 72.5% (95% CI = 67.8% – 76.8%) of the elderly had been taking at least one PIM with the median number of PIMs being 1 (1, 2) items. In the elderly aged 60 – 74 years, the top three PIMs included amlodipine (18.7%), orphenadrine (9.9%), and diclofenac and nifedipine SR (9.1% each). In the elderly aged ³ 75 years, the top three PIMs were amlodipine (18.8%), nifedipine SR (11.6%), and orphenadrine (9.9%). Factors associated with PIMs use included having income ³ 1,000 baht per month (adjusted OR = 1.83, 95% CI = 1.07 – 3.13, p = 0.028), using dietary supplement/herbal medicine (adjusted OR = 3.12, 95% CI = 1.16 – 8.39, p = 0.025), minor polypharmacy (5 – 9 items) (adjusted OR = 2.45, 95% CI = 1.40 – 4.29, p = 0.002) and major polypharmacy (³ 10 items) (adjusted OR = 6.18, 95% CI = 1.68 – 22.74, p = 0.007). PIMs use was highly prevalent among Thai elderly residing in urban communities. Factors associated with PIMs use found in this study included high income, dietary supplement/herbal medicine use, and polypharmacy.


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Original Research Articles