EFFICACY OF NATURAL TRYPTOPHAN FROM LOTUS SEEDS ON SLEEP QUALITY AND OTHER SLEEP-RELATED PARAMETERS

Authors

  • Jutawan Nuanchankong Department of Nutrition and Dietetics, Faculty of Science and Technology,Valaya Alongkorn Rajabhat University under the Royal Patronage, Pathumthani
  • Pattamaporn Jaroennon Department of Nutrition and Dietetics, Faculty of Science and Technology,Valaya Alongkorn Rajabhat University under the Royal Patronage, Pathumthani
  • Sakunta Manakla Department of Nutrition and Dietetics, Faculty of Science and Technology,Valaya Alongkorn Rajabhat University under the Royal Patronage, Pathumthani

DOI:

https://doi.org/10.14456/tbps.2022.17

Keywords:

lotus seeds, tryptophan, sleep quality

Abstract

This study aimed to evaluate the efficacy of lotus seeds consumption on sleep quality and other sleep-related parameters. Thirteen participants consumed 80 g of roasted lotus seeds that contained approximately 250 mg of tryptophan daily for 4 weeks. Subjective sleep measurement (Thai version of the Pittsburgh Sleep Quality Index (Thai-PSQI)), Daily Sleep Diary, Stress Test Questionnaire (ST5), the Revised Piper Fatigue Scale (RPFS) and nutritional assessment including anthropometric and dietary assessments were tools for the evaluation. Daily 80 g of roasted lotus seeds consumption for 4 weeks significantly improved sleep quality (6.2 ± 2.5), habitual sleep efficiency (92.9 ± 5.8 %), total sleep time (6.8 ± 0.8 h), sleep onset latency (36.9 ± 13.1 min) and stress (5.7 ± 3.4). Moreover, day-time dysfunction, feeling refreshed after waking up, and fatigue also improved. The study recommends that consumption of roasted lotus seeds, which contain natural tryptophan, is beneficial to sleep and can potentially relieve insomnia.

References

Angelone AM, Mattei A, Sbarbati M, Di Orio F. Prevalence and correlates for self-reported sleep problems among nursing students. J Prev Med Hyg. 2011;52(4):201-8.

Ranasinghe, Abigail Nirandhi, R. Gayathri and V. Vishnu Priya. Awareness of effects of sleep deprivation among college students. Drug Invent Today. 2018 ;10(9):1806-9.

Buboltz WC Jr, Brown F, Soper B. Sleep habits and patterns of college students: a preliminary study. J Am Coll Health. 2001;50(3):131-5.

Kanova M, Kohout P. Tryptophan: A unique role in the critically ill. Int J Mol Sci 2021, 22(21), 11714.

Wurtman RJ, Wurtman JJ, Regan MM, McDermott JM, Tsay RH, Breu JJ. Effects of normal meals rich in carbohydrates or proteins on plasma tryptophan and tyrosine ratios. Am J Clin Nutr. 2003;77(1):128-32.

Peuhkuri K, Sihvola N, Korpela R. Diet promotes sleep duration and quality. Nutr Res. 2012;32(5):309-19.

Siritientong T. Evidence-based complementary and alternative medicine for insomnia. Thai Bull Pharm Sci. 2017; 12(2):49-67.

Punia Bangar S, Dunno K, Kumar M, Mostafa H, Maqsood S. A comprehensive review on lotus seeds (Nelumbo nucifera Gaertn.): Nutritional composition, health-related bioactive properties, and industrial applications. J Funct Foods. 2022;89(104937):104937.

Arooj M, Imran S, Inam-Ur-Raheem M, Rajoka MSR, Sameen A, Siddique R, et al. Lotus seeds (Nelumbinis semen) as an emerging therapeutic seed: A comprehensive review. Food Sci Nutr. 2021;9(7):3971-87.

Jo K, Choi HS, Jeon S, Ahn CW, Suh HJ. Nelumbo nucifera Seed Extract Promotes Sleep in Drosophila melanogaster. Biol Pharm Bull. 2018;41(3):399-408.

Jo K, Kim S, Hong K-B, Suh HJ. Nelumbo nucifera promotes non-rapid eye movement sleep by regulating GABAergic receptors in rat model. J Ethnopharmacol. 2021;267(113511): 113511.

Hudson C, Hudson SP, Hecht T, MacKenzie J. Protein source tryptophan versus pharmaceutical grade tryptophan as an efficacious treatment for chronic insomnia. Nutr Neurosci. 2005;8(2):121-7.

Wada K, Yata S, Akimitsu O, Krejci M, Noji T, Nakade M, et al. A tryptophan-rich breakfast and exposure to light with low color temperature at night improve sleep and salivary melatonin level in Japanese students. J Circadian Rhythms. 2013;11(4):1-9.

The American Heart Association. Suggested Servings from Each Food Group[Internet]. [cited 2020 Nov 14]. Available from: https://www.heart.org/en/healthy-living/healthy-eating/eat-smart/nutrition-basics/suggested-servings-from-each-food-group

Sitasuwan T, Bussaratid S, Ruttanaumpawan P, Chotinaiwattarakul W. Reliability and validity of the Thai version of the Pittsburgh Sleep Quality Index. J Med Assoc Thai. 2014;97(3):57-67.

Lin H-H, Tsai PS, Fang SC, Liu JF. Effect of kiwifruit consumption on sleep quality in adults with sleep problems. Asia Pac J Clin Nutr. 2011;20(2):169-74.

Cohen J. Statistical Power Analysis for the Behavioral Sciences. 2nd ed. Hillsdale, New Jersey: Lawrence Erlbaum Associates Publishers; 1988.

Bureau of Nutrition, Department of Health, Ministry of Public Health, Thailand. Amino acid content of Thai food. 3rd ed. [Internet]. Nonthaburi; [cited 2020 Nov 11]. Available from: https://nutrition2.anamai.moph.go.th/th/thai-food-composition-table/download?id=39845&mid=31993&mkey=m_document&lang=th&did=13915

Silpakit O, Silpakit C. A thai version of mindfulness questionnaire: Srithanya Sati scale. East Asian Arch Psychiatry. 2014;24(1):23–9.

Piper BF, Dibble SL, Dodd MJ, Weiss MC, Slaughter RE. The revise Piper fatigue scale: Psychometric evalution in women with breast cancer. Oncol Nurs Forum. 1998;25:677-84.

Gibson RS. Principles of Nutritional Assessment. 2nd ed, New York: Oxford University Press Inc.; 2005.

Institute of Nutrition, Mahidol university. Nutrient calculation computer software INMUCAL-Nutrients V3 database NB1. Nakornpathom; 2013.

Fukushige H, Fukuda Y, Tanaka M, Inami K, Wada K, Tsumura Y, et al. Effects of tryptophan-rich breakfast and light exposure during the daytime on melatonin secretion at night. J Physiol Anthropol. 2014;33(1):1-9.

Palego L, Betti L, Rossi A, Giannaccini G. Tryptophan biochemistry: Structural, nutritional, metabolic, and medical aspects in humans. Journal of Amino Acids. 2016;2016(1):1-13.

Zuraikat FM, Wood RA, Barragán R, St-Onge M-P. Sleep and diet: Mounting evidence of a cyclical relationship. Annu Rev Nutr. 2021;41(1):309–32.

Chaput JP, Dutil C, Sampasa-Kanyinga H. Sleeping hours: what is the ideal number and how does age impact this? Nat Sci Sleep. 2018; 27(10):421-30.

Ohayon M.M. et al.National Sleep Foundation's sleep quality recommendations: first report. Sleep Health. 2017;3(1):6-19.

Morssinkhof M.W.L. et al. Associations between sex hormones, sleep problems and depression: A systematic review. Neurosci Biobehav Rev. 2020;118:669-680.

Downloads

Published

2022-08-30

Issue

Section

Original Research Articles