The Possible Uses of Polyphenols-Rich Diets in Postprandial Glycemic Control
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Jan 1, 2020
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Abstract
Polyphenols in plant diets were found to be beneficial to human health in several aspects, including postprandial glycemic control by the inhibition of carbohydrate digestion and absorption. This effect is similar to acarbose, a medicine used in diabetics for glycemic control purpose. Therefore, there is a possibility of using polyphenols-rich sources in the production of medicines, supplements and functional foods which can be a part of daily diet. This review study summarized the knowledge about the relation between polyphenols-rich diets and postprandial glycemic control, including possible mechanisms, in vitro studies and human studies, especially in an aspect of receiving polyphenols in a form of normal diets. The result found that polyphenols-rich diets extract showed positive results in many in vitro studies. However, the results among human studies using polyphenols sources in the form and amount that present in daily diet were contradictory. More human studies should be undertaken, especially in aspects of types, forms and doses of polyphenols-rich diets that lead to positive results, in order to obtain more evidence for final conclusion.
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Wongvasu, P. (2020). The Possible Uses of Polyphenols-Rich Diets in Postprandial Glycemic Control. Journal of Food Technology, Siam University, 15(1), 1–14. Retrieved from https://li01.tci-thaijo.org/index.php/JFTSU/article/view/210901
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บทความวิชาการ (Academic Article)
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References
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[17] Sangsirimongkolying, R., Supawantanakul, D. and Chalopagorn, P. (2019). Study on the inhibiting effect of alpha-amylase and alpha-glucosidase by local cuisine in Chaibadan district, Lopburi province. Huachiew Clermprakiet Science and Technology journal. 5(1): 73-87.
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[19]Kerimi, A., Nyambe-Silavwe, H., Gauer, J.S., Tomás-Barberán, F.A. and Williamson, G. (2017). Pomegranate juice, but not an extract, confers a lower glycemic response on a high-glycemic index food: randomized, crossover, controlled trials in healthy subjects. The American Journal of Clinical Nutrition. 106(6): 1384-1393.
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[24] da Silva Pinto, M., Kwon, Y.I., Apostolidis, E., Lajolo, F.M., Genovese, M.I. and Shetty, K. (2008). Functionality of bioactive compounds in brazilian strawberry (Fragaria x ananassa Duch.) cultivars: evaluation of hyperglycemia and hypertension potential using in vitro models. Journal of Agricultural and Food Chemistry. 56(12): 4386-4392.
[25] Kwon, Y.I., Apostolidis, E., Kim, Y.C. and Shetty, K. (2007). Health benefits of traditional corn, beans, and pumpkin in vitro studies for hyperglycemia and hypertension management. Journal of Medicinal Food. 10(2): 266-275.
[26] Kwon, Y.I., Apostolidis, E. and Shetty, K. (2008). In vitro studies of eggplant (Solanum melongena) phenolics as inhibitors of key enzymes relevant for type 2 diabetes and hypertension. Bioresource Technology. 99(8): 2981-2988.
[27] Srisawat, R. (2012). Effects of some medicinal plant extracts in the area of Suranaree University of Technology on the activities of lipase, amylase and glucosidase enzymes. Unpublished full research report of Suranaree University of Technology. Nakhon Ratchasima. Thailand.
[28] Kaewpiboon, C. and Supaphon, P. (2019). Antioxidant and in vitro lipase, amylase and alpha-glucosidase inhibitory activities of selected thai medicinal plants. Thai Science and Technology Journal. 27(3): 435-444.
[29] Poungcho, P. and Nualkaew, N. (2013). α-Glucosidase inhibition of Thai local vegetable extracts. Isan Journal of Phamaceutical Science. 9(1):218.
[30] Sae-tan, S. and Kunpanya, P. (2017). Water extract from leaf and stem of white mugwort inhibits enzyme activity of α-amylase and α-glucosidase. Journal of Nutrition Association of Thailand. 52(2): 16-22.
[31] Matsui, T., Ebuchi, S., Kobayashi, M., Fukui, K., Sugita, K., Terahara, N. and Matsumoto, K. (2001). Anti-hyperglycemic effect of diacylated anthocyanin derived from Ipomoea batatas cultivar Ayamurasaki can be achieved through the alpha-glucosidase inhibitory action. Journal of Agricultural and Food Chemistry. 50(25): 7244-7248.
[32] Takayuki, H., Chisato, M., Hitoshi, A., Hanamura, T., Mayama, C. and Aoki. H. (2006). Antihyperglycemic effect of polyphenols from acerola (Malpighia emarginata DC.) Fruit. Bioscience Biotechnology and Biochemistry. 70(8): 1813-1820.
[33] Kim, S.H., Jo, S.H., Kwon, Y.I. and Hwang, J.K. (2011). Effects of onion (Allium cepa L.) extract administration on intestinal α -glucosidases activities and spikes in postprandial blood glucose levels in SD rats model. International Journal of Molecular Sciences. 12(6): 3757-3769.
[34] Tanaka, S., Han, L.-K., Zheng, Y.-N. and Okuda, H. (2004). Effects of the flavonoid fraction from Ginkgo biloba extract on the postprandial blood glucose elevation in rats. Journal of the Pharmaceutical Society of Japan. 124: 605-612.
[35] Jurgoński, A., Billing-Marczak, K., Juśkiewicz, J. and Krotkiewski, M. (2019). Formulation of a mixture of plant extracts for attenuating postprandial glycemia and diet-induced disorders in rats.Molecules (basel, Switzerland). 24(20): 3669.
[36] Brouns, F., Bjorck, I., Frayn, K.N., Gibbs, A.L., Lang, V. ,Slama, G. and Wolever, T.M.S. (2005). Glycaemic index methodology. Nutrition Research Reviews. 18(1): 145-171.
[37] Bryans, J.A., Judd, P.A. and Ellis, P.R. (2007).The effect of consuming instant black tea on postprandial plasma glucose and insulin concentrations in healthy humans. Journal of the American College of Nutrition. 26(5): 471-477.
[38] Suraphad, P., Suklaew, P.O., Ngamukote, S., Adisakwattana, S. and Mäkynen, K. (2017) The effect of isomaltulose together with green tea on glycemic response and antioxidant capacity: a single-blind, crossover study in healthy subjects. Nutrients. 9(5): 464.
[39] Törrönen, R., Kolehmainen, M., Sarkkinen, E., Mykkänen, H. and Niskanen, L. (2012). Postprandial glucose, insulin, and free fatty acid responses to sucrose consumed with blackcurrants and lingonberries in healthy women. The American Journal of Clinical Nutrition. 96(3): 527-533.
[40] Clegg, M. Pratt, M., Meade, C. and Henry, J. (2011). The addition of raspberries and blueberries to a starch-based food does not alter the glycaemic response. The British Journal of Nutrition. 106(3): 335-338.
[41] Törrönen, R., Kolehmainen, M., Sarkkinen, E., Poutanen, K., Mykkänen, H. and Niskanen, L. (2013). Berries reduce postprandial insulin responses to wheat and rye breads in healthy women. The Journal of Nutrition. 143(4): 430-436.
[42] Törrönen, R., Sarkkinen, E., Tapola, N., Hautaniemi, E., Kilpi, K. and Niskanen, L. (2009). Berries modify the postprandial plasma glucose response to sucrose in healthy subjects. The British Journal of Nutrition. 103(8): 1094-1097.
[43] Johnston, K.L., Clifford, M.N. and Morgan, L.M. (2003). Coffee acutely modifies gastrointestinal hormone secretion and glucose tolerance in humans: glycemic effects of chlorogenic acid and caffeine. The American Journal of Clinical Nutrition. 78(4): 728-733.
[44] Balisteiro, D.M., Alezandro, M.R., and Genovese, M.I. (2013). Characterization and effect of clarified araçá (Psidium guineenses Sw.) juice on postprandial glycemia in healthy subjects. Food Science and Technology. 33(SUPPL.1): 66-74.
[45] Nyambe-Silavwe, H. and Williamson, G. (2016). Polyphenol- and fibre-rich dried fruits with green tea attenuate starch-derived postprandial blood glucose and insulin: a randomised, controlled, single-blind, cross-over intervention. British Journal of Nutrition. 116(3): 443-450.
[46] Bryans, J.A., Judd, P.A. and Ellis, P.R. (2007). The effect of consuming instant black tea on postprandial plasma glucose and insulin concentrations in healthy humans. Journal of the American College of Nutrition. 26(5): 471-477.
[47] Castro-Acosta, M.L., Stone, S.G., Mok, J.E., Mhajan, R.K., Fu, C.-I., Lenihan-Geels, G.N., Corpe, C.P. and Hall, W.L. (2017). Apple and blackcurrant polyphenol-rich drinks decrease postprandial glucose, insulin and incretin response to a high-carbohydrate meal in healthy men and women. Journal of Nutritional Biochemistry. 49: 53-62.
[48] Mohan, R., Jose, S., Mulakkal, J., Karpinsky-Semper, D., Swick, A.G. and Krishnakumar, I.M. (2019). Water-soluble polyphenol-rich clove extract lowers pre- and post-prandial blood glucose levels in healthy and prediabetic volunteers: an open label pilot study. Bmc Complementary and Alternative Medicine. 19(1): 1-9.
[49] König, A., Schwarzinger, B., Stadlbauer, V., Lanzerstorfer, P., Iken, M., Schwarzinger, C., Kolb, P., Schwarzinger, S., Mörwald, K., Brunner, S., Höglinge,r O., Weghuber, D. and Weghuber, J. (2019). Guava fruit extract prepared by supercritical CO2 extraction inhibits intestinal glucose resorption in a double-blind, randomized clinical study. Nutrients. 11(7). 1512.
[50] Coe, S. and Ryan, L. (2016). Impact of polyphenol-rich sources on acute postprandial glycaemia: a systematic review. Journal of Nutritional Science. 5: e24.
[2] Williamson, G. (2017).The role of polyphenols in modern nutrition. Nutrition Bulletin. 42(3): 226-235.
[3] Williamson, G. (2013). Possible effects of dietary polyphenols on sugar absorption and digestion. MNFR Molecular Nutrition & Food Research. 57(1):48-57.
[4] Wolever, T.M., Jenkins, D.J., Jenkins, A.L. and Josse, R.G. 1991. The glycemic index: methodology and clinical implications. The American journal of clinical nutrition. 54(5): 846-854.
[5] Antonio, C. (2005). Postprandial Hyperglycemia and Diabetes Complications: Is It Time to Treat? Diabetes. 54(1): 1-7.
[6] Dickinson, S., Colagiuri, S., Faramus, E., Petocz, P. and Brand-Miller, J.C. (2002). Postprandial hyperglycemia and insulin sensitivity differ among lean young adults of different ethnicities. The Journal of nutrition. 132(9): 2574-2579.
[7] Srirod, K. and Piyachomkwan, K. (2016). Technology of starch. Kasetsart University Press, Bangkok.
[8] Hanhineva, K., Törrönen, R., Bondia-Pons, I., Jokkala, J., Kolehmainen, M., Mykkänen, H. and Poutanen, K. (2010). Impact of dietary polyphenols on carbohydrate metabolism. International Journal of Molecular Sciences. 11(4): 1365-1402.
[9] Sim, L., Willemsma, C., Mohan, S., Naim, H.Y., Pinto, B.M. and Rose, D.R. (2010). Structural basis for substrate selectivity in human maltase-glucoamylase and sucrase-isomaltase N-terminal domains. The Journal of Biological Chemistry. 285(23): 17763-17770.
[10] Kellett, G. L., Brot-Laroche, E., Mace, O.J. and Leturque, A. (2008). Sugar absorption in the intestine: the role of GLUT2. Annual review of nutrition. 28: 35-54.
[11] Kellett, G.L. and Brot-Laroche, E. (2005). Apical GLUT2: a major pathway of intestinal sugar absorption. Diabetes. 54(10): 3056-3062.
[12] Pinés Corrales, P.J., Bellido Castañeda, V. and Ampudia-Blasco, F.J. (2018). Update on postprandial hyperglycemia: The pathophysiology, prevalence, consequences and implications of treating diabetes. RCENG Revista Clínica Española (English Edition).
[13] Wright, E.Jr., Scism-Bacon, J.L. and Glass, L.C. (2006). Oxidative stress in type 2 diabetes: the role of fasting and postprandial glycaemia. International journal of clinical practice. 60(3): 308-314.
[14] Ludwig, D.S. (2002). The glycemic index: physiological mechanisms relating to obesity, diabetes, and cardiovascular disease. JAMA. 287(18): 2414-23.
[15] Bonora, E. (2002). Postprandial peaks as a risk factor for cardiovascular disease: Epidemiological perspectives. International journal of clinical practice. Supplement. 129: 5-11.
[16] Gauer, J. S., Tumova, S., Kerimi, A., Williamson, G. and Lippiat, J.D. (2018). Differential patterns of inhibition of the sugar transporters GLUT2, GLUT5 and GLUT7 by flavonoids. Biochemical Pharmacology. 152: 11-20.
[17] Sangsirimongkolying, R., Supawantanakul, D. and Chalopagorn, P. (2019). Study on the inhibiting effect of alpha-amylase and alpha-glucosidase by local cuisine in Chaibadan district, Lopburi province. Huachiew Clermprakiet Science and Technology journal. 5(1): 73-87.
[18] Rasouli, H., Hosseini-Ghazvini, S. M.-B., Adibi, H. and Khodarahmi, R. (2017). Differential α-amylase/α-glucosidase inhibitory activities of plant-derived phenolic compounds: a virtual screening perspective for the treatment of obesity and diabetes. Food & Function. 8(5): 1942-1954.
[19]Kerimi, A., Nyambe-Silavwe, H., Gauer, J.S., Tomás-Barberán, F.A. and Williamson, G. (2017). Pomegranate juice, but not an extract, confers a lower glycemic response on a high-glycemic index food: randomized, crossover, controlled trials in healthy subjects. The American Journal of Clinical Nutrition. 106(6): 1384-1393.
[20] Manzano, S. and Williamson, G. (2010). Polyphenols and phenolic acids from strawberry and apple decrease glucose uptake and transport by human intestinal Caco-2 cells. Molecular Nutrition & Food Research. 54(12): 1773-1780.
[21] Koh, L.W., Lin, L., Loo, Y.Y., Kasapis, S. and Huang, D. (2010). Evaluation of different teas against starch digestibility by mammalian glycosidases. Journal of agricultural and food chemistry. 58(1): 148-154.
[22] Kashket, S. and Paolino, V. J. (1988). Inhibition of salivary amylase by water-soluble extracts of tea. Archives of Oral Biology Archives of Oral Biology. 33(11): 845-846.
[23] McDougall, G.J., Shpiro, F., Dobson, P., Smith, P., Blake, A. and Stewart, D. (2005). Different polyphenolic components of soft fruits inhibit -amylase and -glucosidase. Journal of agricultural and food chemistry. 53(7): 2760-2766.
[24] da Silva Pinto, M., Kwon, Y.I., Apostolidis, E., Lajolo, F.M., Genovese, M.I. and Shetty, K. (2008). Functionality of bioactive compounds in brazilian strawberry (Fragaria x ananassa Duch.) cultivars: evaluation of hyperglycemia and hypertension potential using in vitro models. Journal of Agricultural and Food Chemistry. 56(12): 4386-4392.
[25] Kwon, Y.I., Apostolidis, E., Kim, Y.C. and Shetty, K. (2007). Health benefits of traditional corn, beans, and pumpkin in vitro studies for hyperglycemia and hypertension management. Journal of Medicinal Food. 10(2): 266-275.
[26] Kwon, Y.I., Apostolidis, E. and Shetty, K. (2008). In vitro studies of eggplant (Solanum melongena) phenolics as inhibitors of key enzymes relevant for type 2 diabetes and hypertension. Bioresource Technology. 99(8): 2981-2988.
[27] Srisawat, R. (2012). Effects of some medicinal plant extracts in the area of Suranaree University of Technology on the activities of lipase, amylase and glucosidase enzymes. Unpublished full research report of Suranaree University of Technology. Nakhon Ratchasima. Thailand.
[28] Kaewpiboon, C. and Supaphon, P. (2019). Antioxidant and in vitro lipase, amylase and alpha-glucosidase inhibitory activities of selected thai medicinal plants. Thai Science and Technology Journal. 27(3): 435-444.
[29] Poungcho, P. and Nualkaew, N. (2013). α-Glucosidase inhibition of Thai local vegetable extracts. Isan Journal of Phamaceutical Science. 9(1):218.
[30] Sae-tan, S. and Kunpanya, P. (2017). Water extract from leaf and stem of white mugwort inhibits enzyme activity of α-amylase and α-glucosidase. Journal of Nutrition Association of Thailand. 52(2): 16-22.
[31] Matsui, T., Ebuchi, S., Kobayashi, M., Fukui, K., Sugita, K., Terahara, N. and Matsumoto, K. (2001). Anti-hyperglycemic effect of diacylated anthocyanin derived from Ipomoea batatas cultivar Ayamurasaki can be achieved through the alpha-glucosidase inhibitory action. Journal of Agricultural and Food Chemistry. 50(25): 7244-7248.
[32] Takayuki, H., Chisato, M., Hitoshi, A., Hanamura, T., Mayama, C. and Aoki. H. (2006). Antihyperglycemic effect of polyphenols from acerola (Malpighia emarginata DC.) Fruit. Bioscience Biotechnology and Biochemistry. 70(8): 1813-1820.
[33] Kim, S.H., Jo, S.H., Kwon, Y.I. and Hwang, J.K. (2011). Effects of onion (Allium cepa L.) extract administration on intestinal α -glucosidases activities and spikes in postprandial blood glucose levels in SD rats model. International Journal of Molecular Sciences. 12(6): 3757-3769.
[34] Tanaka, S., Han, L.-K., Zheng, Y.-N. and Okuda, H. (2004). Effects of the flavonoid fraction from Ginkgo biloba extract on the postprandial blood glucose elevation in rats. Journal of the Pharmaceutical Society of Japan. 124: 605-612.
[35] Jurgoński, A., Billing-Marczak, K., Juśkiewicz, J. and Krotkiewski, M. (2019). Formulation of a mixture of plant extracts for attenuating postprandial glycemia and diet-induced disorders in rats.Molecules (basel, Switzerland). 24(20): 3669.
[36] Brouns, F., Bjorck, I., Frayn, K.N., Gibbs, A.L., Lang, V. ,Slama, G. and Wolever, T.M.S. (2005). Glycaemic index methodology. Nutrition Research Reviews. 18(1): 145-171.
[37] Bryans, J.A., Judd, P.A. and Ellis, P.R. (2007).The effect of consuming instant black tea on postprandial plasma glucose and insulin concentrations in healthy humans. Journal of the American College of Nutrition. 26(5): 471-477.
[38] Suraphad, P., Suklaew, P.O., Ngamukote, S., Adisakwattana, S. and Mäkynen, K. (2017) The effect of isomaltulose together with green tea on glycemic response and antioxidant capacity: a single-blind, crossover study in healthy subjects. Nutrients. 9(5): 464.
[39] Törrönen, R., Kolehmainen, M., Sarkkinen, E., Mykkänen, H. and Niskanen, L. (2012). Postprandial glucose, insulin, and free fatty acid responses to sucrose consumed with blackcurrants and lingonberries in healthy women. The American Journal of Clinical Nutrition. 96(3): 527-533.
[40] Clegg, M. Pratt, M., Meade, C. and Henry, J. (2011). The addition of raspberries and blueberries to a starch-based food does not alter the glycaemic response. The British Journal of Nutrition. 106(3): 335-338.
[41] Törrönen, R., Kolehmainen, M., Sarkkinen, E., Poutanen, K., Mykkänen, H. and Niskanen, L. (2013). Berries reduce postprandial insulin responses to wheat and rye breads in healthy women. The Journal of Nutrition. 143(4): 430-436.
[42] Törrönen, R., Sarkkinen, E., Tapola, N., Hautaniemi, E., Kilpi, K. and Niskanen, L. (2009). Berries modify the postprandial plasma glucose response to sucrose in healthy subjects. The British Journal of Nutrition. 103(8): 1094-1097.
[43] Johnston, K.L., Clifford, M.N. and Morgan, L.M. (2003). Coffee acutely modifies gastrointestinal hormone secretion and glucose tolerance in humans: glycemic effects of chlorogenic acid and caffeine. The American Journal of Clinical Nutrition. 78(4): 728-733.
[44] Balisteiro, D.M., Alezandro, M.R., and Genovese, M.I. (2013). Characterization and effect of clarified araçá (Psidium guineenses Sw.) juice on postprandial glycemia in healthy subjects. Food Science and Technology. 33(SUPPL.1): 66-74.
[45] Nyambe-Silavwe, H. and Williamson, G. (2016). Polyphenol- and fibre-rich dried fruits with green tea attenuate starch-derived postprandial blood glucose and insulin: a randomised, controlled, single-blind, cross-over intervention. British Journal of Nutrition. 116(3): 443-450.
[46] Bryans, J.A., Judd, P.A. and Ellis, P.R. (2007). The effect of consuming instant black tea on postprandial plasma glucose and insulin concentrations in healthy humans. Journal of the American College of Nutrition. 26(5): 471-477.
[47] Castro-Acosta, M.L., Stone, S.G., Mok, J.E., Mhajan, R.K., Fu, C.-I., Lenihan-Geels, G.N., Corpe, C.P. and Hall, W.L. (2017). Apple and blackcurrant polyphenol-rich drinks decrease postprandial glucose, insulin and incretin response to a high-carbohydrate meal in healthy men and women. Journal of Nutritional Biochemistry. 49: 53-62.
[48] Mohan, R., Jose, S., Mulakkal, J., Karpinsky-Semper, D., Swick, A.G. and Krishnakumar, I.M. (2019). Water-soluble polyphenol-rich clove extract lowers pre- and post-prandial blood glucose levels in healthy and prediabetic volunteers: an open label pilot study. Bmc Complementary and Alternative Medicine. 19(1): 1-9.
[49] König, A., Schwarzinger, B., Stadlbauer, V., Lanzerstorfer, P., Iken, M., Schwarzinger, C., Kolb, P., Schwarzinger, S., Mörwald, K., Brunner, S., Höglinge,r O., Weghuber, D. and Weghuber, J. (2019). Guava fruit extract prepared by supercritical CO2 extraction inhibits intestinal glucose resorption in a double-blind, randomized clinical study. Nutrients. 11(7). 1512.
[50] Coe, S. and Ryan, L. (2016). Impact of polyphenol-rich sources on acute postprandial glycaemia: a systematic review. Journal of Nutritional Science. 5: e24.