Metastasis of Amelanotic Melanoma of Unknown Origin in the Parotid Gland: A Case Report with Literature Review


  • Pattama Punyavong




Background and Objectives: Malignant melanoma of parotid gland is an extremely rare, almost case represent metastases from a head and neck melanoma or unknown primary origin. The treatment is still challenging and the prognosis is very poor. The aim of this study was to present a rare case of a metastasis of an amelanotic melanoma of unknown origin in the parotid gland.

Method: A single case report.

Results: A 61-year-old male present with painless mass at left parotid gland for 1 year, physical examination and CT scan showed solid mass located at superficial lobe of left parotid gland. The pathological diagnosis after performed superficial parotidectomy was amelanotic malignant melanoma, possibility of metastasis melanoma from other primary lesion. Complete physical examination and PET-CT were performed to find out primary tumor and other metastatic lesion, the results showed no primary origin but highly suspicious of right cervical lymph node metastasis. Patient underwent bilateral modified radical neck dissection and pathological diagnosis was no tumor metastasis. Patient received adjuvant radiotherapy(60 Gy) with satisfied functional and aesthetic outcome without signs or symptoms of recurrence for 30 months

Conclusion: Metastatic parotid melanoma from unknown primary tumor is rare phenomenon and prognosis is worse. There is need of early detection, adequate and aggressive treatment in view of poor prognosis. Multidisciplinary treatment approach for adequate local control and improved survival as well as quality of life.


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How to Cite

Punyavong P. Metastasis of Amelanotic Melanoma of Unknown Origin in the Parotid Gland: A Case Report with Literature Review. SRIMEDJ [Internet]. 2018 Oct. 6 [cited 2024 May 25];33(6):609-14. Available from: