Relationships between Heart Rate Variability, Motor Impairments and Level of disability in Chronic Ischemic Stroke Patients

Authors

  • Waroonnapa Srisoparb Department of Physical Thaerapy, Naresuan University
  • ณัฐชยา ชนแดน Department of Physical Therapy, Faculty of Allied Health Sciences, Naresuan University
  • พรรณรายณ์ พลูศิริ Department of Physical Therapy, Faculty of Allied Health Sciences, Naresuan University
  • สุกัญญา ศรีสวัสดิ์ Department of Physical Therapy, Faculty of Allied Health Sciences, Naresuan University
  • สุจิตรา มีสีบัว Department of Physical Therapy, Faculty of Allied Health Sciences, Naresuan University
  • โอฬาร อิสริยะพันธุ์ Department of Physical Therapy, Faculty of Allied Health Sciences, Naresuan University
  • ปฏิวัติ โชติมล Department of Cardio-Thoracic Technology, Faculty of Allied Health Sciences, Naresuan University
  • ดวงนภา รุ่งพิบูลโสภิษฐ์ Division of Neurology, Department of Medicine, Faculty of Medical, Naresuan University
  • เบญจรัตน์ แสงทอง Faculty of Physical Therapy and Sport Medicine, Rangsit University
  • เกริกเกียรติ จินดา Department of Physiology, Faculty of Medical Science, Naresuan University

Keywords:

Heart Rate Variability, Ischemic Stroke, Motor Impairment, Disability

Abstract

Background and objective:  Alteration in the autonomic cardiovascular control that is measured by heart rate variability (HRV) is associated with motor impairments of acute chronic stroke patients. The purposes of this study was to investigate the association between cardiac autonomic function, motor impairments and disability level in chronic ischemic stroke patients.

Methods: Thirteen participants aged between 40-75 years old, suffered from stroke for 6 months to 5 years, were able to stand for at least 5 minute and could follow 2 steps command were recruited in to the study. Participant were evaluated HRV for 20 mins in supine resting position. Upper and lower extremities motor impairments and level of disability were assessed by Fugl-Meyer assessment (FMA) and modified Rankin Scale (mRS), respectively. Spearman’s correlation coefficients were used to investigate the association between outcome measures. Differences were considered statistically significant at p < 0.05.

Result: The results showed a moderate positive and significant correlation between upper extremity impairment (FMA-UEs) and LF (nu) (r = 0.622; p = 0.02), and LF/HF ratio (r = 0.561; p = 0.04). Furthermore, there was a strong negative and significant correlations between mRS and LF (nu) (r = -0.855; p < 0.001), and LF/HF ratio (r = -0.711; p = 0.006).

Conclusion: HRV of chronic ischemic stroke is associated with motor impairments and level of disability.

References

1. Venketasubramanian N, Yoon BW, Pandian J, Navarro JC. Stroke Epidemiology in South, East, and South-East Asia: A Review. JoS. 2017; 19(3): 286-94.
2. Al-Qudah ZA, Yacoub HA, Souayah N. Disorders of the Autonomic Nervous System after Hemispheric Cerebrovascular Disorders: An Update. J Vasc Interv Neurol. 2015; 8(4): 43-52.
3. Chen Z, Venkat P, Seyfried D, Chopp M, Yan T, Chen J. Brain-Heart Interaction: Cardiac Complications After Stroke. Circulation research. 2017; 121(4): 451-68.
4. Rajendra Acharya U, Paul Joseph K, Kannathal N, Lim CM, Suri JS. Heart rate variability: a review. Med Biol Eng Comput. 2006; 44(12): 1031-51.
5. Katz-Leurer M, Shochina M. Heart Rate Variability (HRV) parameters correlate with motor impairment and aerobic capacity in stroke patients. NeuroRehabilitation. 2005; 20(2): 91-5.
6. Cohen J. Statistical Power Analysis for the Behavioral Sciences ed 2. Hillsdale. NJ: Lawrence Erlbaum Associates, 1988.
7. Sethi A, Callaway CW, Sejdic E, Terhorst L, Skidmore ER. Heart Rate Variability Is Associated with Motor Outcome 3-Months after Stroke. J Stroke Cerebrovasc Dis: the official journal of National Stroke Association. 2016; 25(1): 129-35.
8. Pagamas Piriyaprasarth Department of Physical Therapy FoAHS, Thammasat University. Stroke Assessment Tools. 2016; 38(3).
9. Geert Sulter CS, and Jacques De Keyser. Use of the Barthel Index and Modified Rankin Scale in Acute Stroke Trials. Stroke. 1999; 30:8.
10. สุคนธสรรพ์ อ. Cardiovascular medicine: The new balance. พิมพ์ครั้งที่ 1. ed. ศรัณย์ ค, editor. เชียงใหม่: คณะแพทยศาสตร์ มหาวิทยาลัยเชียงใหม่; 2555.
11. Gujjar AR, Sathyaprabha TN, Nagaraja D, Thennarasu K, Pradhan N. Heart rate variability and outcome in acute severe stroke: role of power spectral analysis. Neurocrit Care. 2004; 1(3): 347-53.
12. Arad M, Abboud S, Radai MM, Adunsky A. Heart rate variability parameters correlate with functional independence measures in ischemic stroke patients. J Electrocardiol. 2002; 35: 243-6.
13. Adams HP, Jr., Bendixen BH, Kappelle LJ, Biller J, Love BB, Gordon DL, et al. Classification of subtype of acute ischemic stroke. Stroke. 1993; 24(1): 35-41.

Published

2022-01-25

How to Cite

1.
Srisoparb W, ชนแดน ณ, พลูศิริ พ, ศรีสวัสดิ์ ส, มีสีบัว ส, อิสริยะพันธุ์ โ, โชติมล ป, รุ่งพิบูลโสภิษฐ์ ด, แสงทอง เ, จินดา เ. Relationships between Heart Rate Variability, Motor Impairments and Level of disability in Chronic Ischemic Stroke Patients. SRIMEDJ [Internet]. 2022 Jan. 25 [cited 2024 Nov. 5];35(6). Available from: https://li01.tci-thaijo.org/index.php/SRIMEDJ/article/view/226780

Issue

Vol. 35 No. 6 (2020): November - December

Section

Original Articles

License

Copyright (c) 2020 Srinagarind Medical Journal

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.