Factors Associated with Pulmonary Tuberculosis among Diabetic Patients in Ban Fang Hospital, Khon Kaen Province
Keywords:
เบาหวาน วัณโรคปอด; ค่าระดับน้ำตาลในเลือดหลังอดอาหาร, Diabetes Mellitus type 2; pulmonary tuberculosis; fasting blood sugarAbstract
Background and Objective: Poor control diabetic patients are at risk of various infections including tuberculosis (TB). This study aimed at studying factors associated with pulmonary tuberculosis infection in diabetic patients
Method: An unmatched case-control study was conducted among type 2 diabetes mellitus (T2DM) patients in Ban Fang hospital, Khon Kaem from October 1st, 2012 to April 30th, 2019. The study group included all T2DM patients who were diagnosed with pulmonary TB, where as the control group were T2DM patients without pulmonary TB diagnosis. Subjects in control group were randomly selected into a ratio 1:2 of case per control. Data collections were performed by reviewing medical records of the hospital database. Data were analyzed using descriptive and analytic approaches such as frequency, percentage, Pearson Chi-square test, Independent-Samples T-test, Odds ratio and multiple logistic regression.
Results: A total of 210 subjects were selected comprising 68 cases of study groupand 142 case of control group. The factors which were significantly related to pulmonary TB among diabetic patients included: FBS ≥180 mg/dl (Adjusted OR = 5.63, 95% CI: 2.61-12.16); BMI<23 kg/m2 (Adjusted OR = 4.86, 95% CI: 2.18-10.84); receiving insulin injection (Adjusted OR = 0.31, 95% CI: 0.13-0.74) and male (Adjusted OR = 2.28, 95% CI: 1.06-4.88).
Conclusion: T2DM patients with high FBS, normal or low BMI and male gender were at high risk of pulmonary TB infection, while patients with history of taking insulin injection were at lower risk.
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