Complications of Liver Transplantation with Successful Treatment by Interventional Radiology Techniques

Authors

  • Jitraporn Wongwiwatchai Department of Radiology, Faculty of Medicine, Khon Kaen University
  • Virin Bejrachandra Department of Radiology, Faculty of Medicine, Khon Kaen University
  • Vivian Klungboonkrong Department of Radiology, Faculty of Medicine, Khon Kaen University
  • Anucha Ahooja Department of Radiology, Faculty of Medicine, Khon Kaen University
  • Arunnit Boonrod Department of Radiology, Faculty of Medicine, Khon Kaen University

Keywords:

Liver transplantation; complication; interventional radiology

Abstract

Background and Objective: Liver transplantation is a treatment option for end-stage liver disease and acute liver failure. Early detection and treatment of postoperative complications have increased survival rates after liver transplantation. The objective of this study was to evaluate efficacy of the interventional radiology procedures in treatment of liver transplant complications.

Material and methods: This retrospective study included 13 patients with post liver transplantation related complications, which were treated with interventional radiology procedures from July 2013 to October 2018. Demographic data, indications for liver transplantation, type of liver transplantation, liver transplantation related complications, onset of complications, interventional radiology procedures and result of treatment were collected.

Results: Between July 2013 to October 2018, 13 patients undergoing 27 procedures were identified, including venoplasty for inferior vena cava and portal vein stenosis (n=3), angioplasty and stent placement without/with thrombolysis for hepatic artery stenosis and hepatic artery thrombosis (n=3), percutaneous transhepatic biliary drainage related procedures (insertion, exchange, and irrigation) for biliary stricture (n=9) and percutaneous drainage related procedures (insertion and exchange) for intraabdominal collections (n=12). Technical and clinical success rates were 100% and 96.3%, respectively.

Conclusion: Interventional radiology procedures have an important role in the management of postoperative complications of liver transplantation under non-operative and minimally invasive techniques with high technical and clinical success rates.

References

1. Thai Transplantation Society.. THAI TRANSPLANT CARE (TTC) LIVER. (2015). [cited May 25, 2020]. Available from: http://www.transplantthai.org/upload/170815114538293_MNB.pdf
2. Song ATW, Avelino-Silva VI, Pecora RAA, Pugliese V, D’Albuquerque LAC, Abdala E. Liver transplantation: Fifty years of experience. World J Gastroenterol 2014; 20(18): 5363–5374.
3. OPTN/SRTR 2016 Annual Data Report: Liver - Kim - 2018 - American Journal of Transplantation - Wiley Online Library [Internet]. [cited May 25, 2020]. Available from: https://onlinelibrary.wiley.com/doi/full/10.1111/ajt.14559
4. Castroagudín JF, Molina E, Bustamante M, Tomé S, Otero E, Martínez J, et al. Orthotopic liver transplantation for hepatocellular carcinoma: a thirteen-year single-center experience. Transplant Proc 2008; 40(9): 2975–2977.
5. Piardi T, Lhuaire M, Bruno O, Memeo R, Pessaux P, Kianmanesh R, et al. Vascular complications following liver transplantation: A literature review of advances in 2015. World J Hepatol 2016; 8(1): 36–57.
6. Pérez-Saborido B, Pacheco-Sánchez D, Barrera-Rebollo A, Asensio-Díaz E, Pinto-Fuentes P, Sarmentero-Prieto JC, et al. Incidence, management, and results of vascular complications after liver transplantation. Transplant Proc 2011; 43(3): 749–750.
7. Pascher A, Neuhaus P. Bile duct complications after liver transplantation. Transpl Int 2005; 18(6): 627–642.
8. Andrews JC. Vascular complications following liver transplantation. Semin Intervent Radiol 2004;21(4): 221–233.
9. Endovascular Treatment of Hepatic Artery Stenosis After Liver Transplantation - PubMed [Internet]. [cited Jun 19, 2020]. Available from: https://pubmed.ncbi.nlm.nih.gov/23332988/
10. Miraglia R, Maruzzelli L, Caruso S, Milazzo M, Marrone G, Mamone G, et al. Interventional radiology procedures in adult patients who underwent liver transplantation. World J Gastroenterol 2009; 15(6): 684–693.
11. Amesur NB, Zajko AB. Interventional radiology in liver transplantation. Liver Transpl 2006; 12(3): 330–351.
12. Settmacher U, Nüssler N, Glanemann M, Haase R, Heise M, Bechstein W, et al. Venous complications after orthotopic liver transplantation. Clinical Transplantation 2000; 14(3): 235–241.
13. Mehrzad H, Mangat K. The Role of Interventional Radiology in Treating Complications following Liver Transplantation. ISRN Hepatol [Internet]. 2012 Dec 3 [cited May 25, 2020];2013. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890878/. doi: 10.1155/2013/696794
14. Kothary N, Patel AA, Shlansky-Goldberg RD. Interventional radiology: management of biliary complications of liver transplantation. Semin Intervent Radiol 2004; 21(4): 297–308.

Downloads

Published

2020-09-08

How to Cite

1.
Wongwiwatchai J, Bejrachandra V, Klungboonkrong V, Ahooja A, Boonrod A. Complications of Liver Transplantation with Successful Treatment by Interventional Radiology Techniques . SRIMEDJ [Internet]. 2020 Sep. 8 [cited 2024 Apr. 19];35(5):561-7. Available from: https://li01.tci-thaijo.org/index.php/SRIMEDJ/article/view/246687

Issue

Section

Original Articles