Outcome of Modified Radical Mastectomy of Breast Cancer in Srinagarind Hospital

Authors

  • Anongporn Wongbuddha Department of Surgery, Faculty of Medicine, Khonkaen University
  • Punnawat Chandrachamnong Department of Surgery, Faculty of Medicine, Khonkaen University
  • Dumnern Vachirodom Department of Surgery, Faculty of Medicine, Khonkaen University
  • Ongart Somintara Department of Surgery, Faculty of Medicine, Khonkaen University

Keywords:

Breast cancer; Modified Radical Mastectomy; 5-year survival rate; 3-year disease- free survival rate

Abstract

Background and Objective: Modified Radical Mastectomy (MRM) is one option for the surgical treatment of breast cancer which is widely used in Srinagarind Hospital. This study aimed to evaluate the outcome of Modified Radical Mastectomy by studying the 5-year survival rate and 3-year disease-free survival rate, complication and risk factor of survival of breast cancer patients at Srinagarind Hospital.

Material and Method: We reviewed the case records of 215 consecutive breast cancer patients who underwent MRM at Srinagarind Hospital, Faculty of medicine, Khonkaen University between January 2004 and December 2007

Result: Of all the 215 patients over the study period, the mean age was 51.1 years old. The most common site of tumor was located by the upper outer quadrant (46.5%). Most patients had Stage II breast cancer: 117 patients (54.4%). The most common operative surgical complication was seroma collection in that was found in seven percent of patients. The 5-year survival rate was 83.6% and the 3-year disease-free survival rate was 78.9%.

Conclusion: The 5-year survival rate of breast cancer patient who underwent MRM was 83.6% and the 3-year disease-free survival rate was 78.9 %.

References

1. World Health Organization International Agency for Research on Cancer. The Global Cancer Observatory. 2018 statistics. [Accessed on January 17, 2019]. Available from http://gco.iarc.fr/today/data/factsheets/populations/900-world-fact-sheets.pdf.
2. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2020. CA Cancer J Clin 2020; 70(1): 7-30. doi: 10.3322/caac.21590.
3. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2019. CA Cancer J Clin 2019; 69(1): 7-34. doi: 10.3322/caac.21551.
4. Kesson EM, Allardice GM, George WD, Burns HJ, Morrison DS. Effects of multidisciplinary team working on breast cancer survival: retrospective, comparative, interventional cohort study of 13 722 women. BMJ 2012; 344: e2718. doi: 10.1136/bmj.e2718.
5. Halverson KJ, Taylor ME, Perez CA, Myerson R, Philpott G, Simpson JR, et al. Survival following breast-conserving surgery and irradiation or modified radical mastectomy in patients with invasive breast cancers with a maximum diameter of 1 cm. Mo Med 1993; 90(12): 759-63.
6. Aphinives P, Punchai S, Vajirodom D, Bhudhisawasdi V. Breast cancer: five-year survival in Srinagarind Hospital, Thailand. J Med Assoc Thai 2010; 93(3): S25-29.
7. Rezaianzadeh A, Peacock J, Reidpath D, Talei A, Hosseini SV, Mehrabani D. Survival analysis of 1148 women diagnosed with breast cancer in Southern Iran. BMC Cancer 2009; 9: 168. doi: 10.1186/1471-2407-9-168.
8. Jan WA, Haq MIU, Haq MA ul, Khan AS. Early complications of modified radical mastectomy with axillary clearance. JPMI 2006; 20(3): 248-251.
9. Chuthapisith S, Permsapaya W, Warnnissorn M, Akewanlop C, Sirivatanauksorn V, Prasarttong Osoth P. Breast cancer subtypes identified by the ER, PR and HER-2 status in Thai women. Asian Pac J Cancer Prev 2012; 13(2): 459-62. doi: 10.7314/apjcp.2012.13.2.459.

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Published

2020-10-16

How to Cite

1.
Wongbuddha A, Chandrachamnong P, Vachirodom D, Somintara O. Outcome of Modified Radical Mastectomy of Breast Cancer in Srinagarind Hospital. SRIMEDJ [Internet]. 2020 Oct. 16 [cited 2024 Apr. 23];35(6):656-61. Available from: https://li01.tci-thaijo.org/index.php/SRIMEDJ/article/view/247315

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Original Articles