Necrotizing fasciitis

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Panu Teeratakulpisarn


           Necrotizing fasciitis is an infection of subcutaneous tissues and fascia, which have continuous aggressive and rapid progression of the disease. The disease is common in Thailand, and common in the extremities, neck, and body.

           Necrotizing fasciitis causes four types of etiology which are post-traumatic, post-operative, idiopathic, and causes by the complication of cutaneous diseases. The bacteriology of disease has three types; polymicrobial, monomicrobial, and microbial from seawater.

           When the pathogen enters subcutaneous tissue, they colonize and cause inflammation. The process results in the necrosis of tissues. The pathognomonic sign is the patient may experience pain out of proportion, local inflammation of the skin, high-grade fever, SIRS, sepsis, and septic shock.

           Treatments of the disease include broad-spectrum antibiotics, aggressive resuscitation, adequate surgical debridement and drainage, post-operative care, wound closure, and rehabilitation, which requires the skill of surgeons.


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Teeratakulpisarn P. Necrotizing fasciitis. SRIMEDJ [Internet]. 2022 Jun. 24 [cited 2022 Nov. 27];37(3):303-12. Available from:
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