Behaviors and Associated Factors of Selection for Self-medication with Non-Prescription Medicines among People in Ongkharak District, Nakhon Nayok Province: Using Paracetamol, Salol et Menthol Mixture, and Oral Rehydration Salts

Authors

  • Pacharaporn Phueanpinit Department of Clinical Pharmacy, Faculty of Pharmacy, Srinakharinwirot University
  • Montira Tantasawat Department of Clinical Pharmacy, Faculty of Pharmacy, Srinakharinwirot University
  • Thanaputt Chaiyasothi Department of Clinical Pharmacy, Faculty of Pharmacy, Srinakharinwirot University
  • Siranan Klanbut Department of Clinical Pharmacy, Faculty of Pharmacy, Srinakharinwirot University

Abstract

Background and objective: Self-medication in the general population for the management of health problems is becoming more widely accessible. This research was to investigate people's behaviors and factors associated with the risk of self-medication, which focused on 3 medication items, i.e. paracetamol, salol et menthol mixture, and oral rehydration salts (ORS).

Method: The cross-sectional study was conducted by using a self-administered questionnaire, which collected data from 480 subjects of the general population in Ongkharak District, Nakhon Nayok province.

Results: The majority of participants used self-medication at least 1-2 times/month (65.6%). Pharmacy was the main source for medication (95.6%), and more than half of all (65.4%) used information sources to aid in decision-making. At about 31.5% of paracetamol user groups demonstrated risk behaviors for paracetamol overdose. Overdose risk was 1.7–4.2 times higher for those with comorbidity, high income, and private sector employment. 75.1% of participants who used salol et menthol mixture were at risk for using it improperly. All occupations, with the exception of students, had a 2.1–4.4-fold higher risk of wrong indication. Approximately 75.5% of participants who used oral rehydration powder had the chance to use it improperly. Self-employed, business owners, and families with children had a 2.1–2.8-fold higher risk of selecting incorrect indications.

Conclusion: The participants had access to various sources of medications and medicine information to support their decision-making. Some participants were at risk of self-medication practices that included drug overdose and inappropriate indication. The risk of self-medication was linked to factors such as income, occupation, comorbidity, and having children in the family.

References

Tesfamariam S, Anand IS, Kaleab G, Berhane S, Woldai B, Habte E, et al. Self-medication with over the counter drugs, prevalence of risky practice and its associated factors in pharmacy outlets of Asmara, Eritrea. BMC Public Health 2019;19:159.

Hedenrud T, Andersson Sundell K, Martinsson J, Håkonsen H. Attitudes towards sales and use of over-the-counter drugs in Sweden in a reregulated pharmacy market: a population-based study. Int J Pharm Pract 2019;27:17-24.

Chautrakarn S, Khumros W, Phutrakool P. Self-medication with over-the-counter medicines among the working age population in metropolitan areas of Thailand. Front Pharmacol 2021;12:726643.

Moreira TA, Alvares-Teodoro J, Barbosa MM, Guerra Júnior AA, Acurcio FA. Use of medicines by adults in primary care: survey on health services in Minas Gerais, Brazil. Rev Bras Epidemiol 2020;23:e200025.

Sánchez-Sánchez E, Fernández-Cerezo FL, Díaz-Jimenez J, Rosety-Rodriguez M, Díaz AJ, Ordonez FJ, et al. Consumption of over-the-counter drugs: prevalence and type of drugs. Int J Environ Res Public Health 2021;18:5530.

Understanding over-the-counter medicines. U.S. Food and Drug administration [serial online] 2018 [cited Jun 11, 2022]. Available from: https://www.fda.gov/drugs/buying-using-medicine-safely/understanding-over-counter-medicines#:~:text=Over%2Dthe%2Dcounter%20medicine%20is,by%20your%20health%20care%20professional.

Locquet M, Honvo G, Rabenda V, Van Hees T, Petermans J, Reginster JY, et al. Adverse health events related to self-medication practices among elderly: a systematic review. Drugs Aging 2017; 34: 359-65.

Adjimatera N. Benefit risk evaluation of Self-care medicine (OTC). CCPE [serial online] 2017 [cited Dec 22, 2021]. Available from: https://ccpe.pharmacycouncil.org/index.php?option=article_detail&subpage=article_detail&id=399

Alsous MM, I Al-Azzam S, Nusair MB, Alnahar SA, Obeidat NA. Self-medication among pregnant women attending outpatients' clinics in northern Jordan-a cross-sectional study. Pharmacol Res Perspect 2021;9:e00735.

Abraham O, Chmielinski J. Adolescents' misuse of over-the-counter medications: the need for pharmacist-led intervention. Innov Pharm 2018;9:1-7.

Lee CH, Chang FC, Hsu SD, Chi HY, Huang LJ, Yeh MK. Inappropriate self-medication among adolescents and its association with lower medication literacy and substance use. PLoS One 2017;12:e0189199.

Subashini N, Udayanga L. Demographic, socio-economic and other associated risk factors for self-medication behaviour among university students of Sri Lanka: a cross sectional study. BMC Public Health 2020;20:613.

Zaprutko T, Koligat D, Michalak M, Wieczorek M, Józiak M, Ratajczak M, et al. Misuse of OTC drugs in Poland. Health Policy 2016;120:875-81.

Fingleton NA, Watson MC, Duncan EM, Matheson C. Non-prescription medicine misuse, abuse and dependence: a cross-sectional survey of the UK general population. J Public Health (Oxf) 2016;38:722-30.

Calamusa A, Di Marzio A, Cristofani R, Arrighetti P, Santaniello V, Alfani S, et al. Factors that influence Italian consumers' understanding of over-the-counter medicines and risk perception. Patient Educ Couns 2012;87:395-401.

Hanna LA, Hughes CM. Public's views on making decisions about over-the-counter medication and their attitudes towards evidence of effectiveness: a cross-sectional questionnaire study. Patient Educ Couns 2011;83:345-51.

Sriuttha P, Suwannaprom P, Niwatananun K. Drug use behaviors and potential risk of hepatotoxicity: A case study of paracetamol in Chiang Mai. Thai Bull Pharm Sci 2018;13:25-40.

Kontogiorgis C, Nena E, Berberoglou E, Moschoni K, Polyzois S, Tselemponis A, et al. Estimating consumers’ knowledge and attitudes towards over-the-counter analgesic medication in Greece in the years of financial crisis: the case of paracetamol. Pain Ther 2016;5:19-28.

Håkonsen H, Hedenrud T. A population-based study of risk perceptions of paracetamol use among Swedes-with a special focus on young adults. Pharmacoepidemiol Drug Saf 2017;26:992-7.

Saengcharoen W, Buasri N, Khantapokha B, Lerkiatbundit S. Public knowledge and factors associated with inappropriate analgesic use: a survey in Thailand. Int J Pharm Pract 2016;24:22-9.

de Oliveira AV, Rocha FT, Abreu SR. Acute liver failure and self-medication. Arq Bras Cir Dig 2014;27:294-7.

Dorji T, Gyeltshen K, Pongpirul K. Rational use of paracetamol among out-patients in a Bhutanese district hospital bordering India: a cross-sectional study. BMC Res Notes 2018;11:660.

Pholmoo N, Bunchorntavakul C. Characteristics and outcomes of acetaminophen overdose and hepatotoxicity in Thailand. J Clin Transl Hepatol. 2019;7:132-9.

Wójta-Kempa M, Krzyżanowski DM. Correlates of abusing and misusing over-the-counter pain relievers among adult population of Wroclaw (Poland). Adv Clin Exp Med 2016;25:349-60.

PubChem Compound Summary for CID 8361, Phenyl salicylate. National Center for Biotechnology Information [serial online] 2022 [cited Jun 11, 2022]. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/Phenyl-salicylate.

Antacids are not salol et menthol mixture. Public & Consumer Affairs Division: Food and Drug Administration [serial online] 2020 [cited Jun 23, 2022]. Available from: https://oryor.com/%E0%B8%AD%E0%B8%A2/detail/media_printing/1849

Chattha IR, Zaffar S, Tariq S, Siddiqui WA, Zaman K, Kamran R, et al. Prevalence of self-medication for acid peptic disease amongst people of Manawa, Lahore. Cureus 2020;12:e6817.

Petcharaburanin P, Saokaew S. Prevalence of unsafe medicines in groceries: a case study in the districs of Lom Kao, Khao Kho and Nam Nao in Petchabun province. TJPP 2019;11:422-30.

Yoopan N, Pumtong S, Duangchan P. Drug management practice in school among personnel in Nakhon Nayok. TJPP 2020;12(2):519-33.

Harris L, Braun M. Electrolytes: oral electrolyte solutions. FP Essent 2017;459:35-8.

Oral rehydration salts (ors): a new reduced osmolarity formulation. World Health Organization [serial online] 2019 [cited April 15, 2022]. Available from: http://rehydrate.org/ors/expert-consultation.html?fbclid=IwAR1iSVrf7qflUPBbiTs0pe-bT6obUr7VtoWF-jczNcG3UScj56j48smRywM

GBD Diarrhoeal Diseases Collaborators. Estimates of global, regional, and national morbidity, mortality, and aetiologies of diarrhoeal diseases: a systematic analysis for the global burden of disease study 2015. Lancet Infect Dis 2017;17:909-48.

Farthing M, Salam MA, Lindberg G, Dite P, Khalif I, Salazar-Lindo E, et al. Acute diarrhea in adults and children: a global perspective. J Clin Gastroenterol 2013;47:12-20.

Cheuvront SN, Kenefick RW, Luque L, Mitchell KM, Vidyasagar S. Are oral rehydration solutions optimized for treating diarrhea? Nutr Health 2021;27:461-5.

Published

2022-12-22

How to Cite

1.
Phueanpinit P, Tantasawat M, Chaiyasothi T, Klanbut S. Behaviors and Associated Factors of Selection for Self-medication with Non-Prescription Medicines among People in Ongkharak District, Nakhon Nayok Province: Using Paracetamol, Salol et Menthol Mixture, and Oral Rehydration Salts. SRIMEDJ [Internet]. 2022 Dec. 22 [cited 2024 Dec. 24];37(6):619-35. Available from: https://li01.tci-thaijo.org/index.php/SRIMEDJ/article/view/255044

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Original Articles