The Proportion of Hepatitis B virus, Measles, and Varicella Immunity Among New Healthcare Personnel at Faculty of Medicine Khon Kaen University, Thailand

Authors

  • Krittin Wipahut Department of Community Medicine, Family Medicine, and Occupational Medicine, Faculty of Medicine, Khon Kaen University
  • Warisa Soonthornvinit Department of Community Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University
  • Naesinee Chaiear Department of Community Medicine, Family Medicine, and Occupational Medicine, Faculty of Medicine, Khon Kaen University

Keywords:

immunity, health care personnel, Hepatitis B, Measle, Varicella

Abstract

Background and Objective: Immunization for preventable diseases was necessary, especially for new healthcare personnel (HCP) who were at risk of nosocomial infection. Therefore, this study aimed to explore the proportions of Hepatitis B virus (HBV), Measles, and Varicella (VZV) immunity of new HCP.

Methods: This research was a retrospective descriptive study. The study population was newly employed HCP of the Faculty of Medicine, Khon Kaen University. The data collected from the preplacement examination program between 1 October 2018 to 31 October 2021 included age, sex, occupation, immunity to HBV, Measles, and VZV. The information was described as number, percentage, average, median, and interquartile range (IQR).

Results: Two thousand, one hundred and fifty-six HCP attended the preplacement examination program through 2018-2021. One hundred and forty-four to 192 were males, and 301-459 were females. Their median age was 24-26 years, and IQR was 5-6 years. The first and second largest occupations were physician 30.4-42.2% and nurse 13.5-30.6%. The average proportion of HBV immunity was 66.8%, Measles immunity was 66.7%, and VZV immunity was 91.6%. The greatest number who had inadequate HBV and Measles immunity were medical assistants, nurses, and physicians occupations.

Conclusion: New HCP had lower HBV and Measles immunity protections. These critical risks should assess before work and promote their coverage.

References

Fiebelkorn AP, Seward JF, Orenstein WA. A global perspective of vaccination of healthcare personnel against measles: Systematic review. Vaccine 2014;32(38):4823–39. doi.org/10.1016/j.vaccine.2013.11.005

World Health Organization. Immunization of health workers [Internet]. 2021 [Cited Nov 1, 2022]. Available from: https://cdn.who.int/media/docs/default-source/immunization/immunization_schedules/immunization-routine-table4.pdf?sfvrsn=714e38d6_4&download=true

Centers for Disease Control and Prevention. Recommended vaccines for healthcare workers [Internet]. Centers for Disease Control and Prevention. 2016 [Cited Nov 1, 2022]. Available from: https://www.cdc.gov/vaccines/adults/rec-vac/hcw.html

Centers for Disease Control and Prevention. Immunization of health care personnel recommendations of the Advisory Committee on Immunization Practices. Vol. 60, Morbidity and Mortality Weekly Report. 2011. 52 p.

Division of vaccine preventable disease, Department of disease control, Ministry of public health. Textbook of vaccine and immunization 2019. 1st edition. Nonthaburi: Work printing, 1992.

Jittpoonkuson T, Wongcong W. Occupational communicable diseases, immunity status study and immunization program arrangement for the BMA general hospital healthcare personnel. Vajira Medical Journal 2015;59(3):15–24.

Wanlapakorn N, Wasitthankasem R, Vichaiwattana P, Auphimai C, Yoocharoen P, Vongpunsawad S, et al. Antibodies against measles and rubella virus among different age groups in Thailand: A population-based serological survey. PLoS One 2019;14(11):1–10. doi.org/10.1371/journal.pone.0225606

Karadeniz A, Akduman Alaşehir E. Seroepidemiology of hepatitis viruses, measles, mumps, rubella and varicella among healthcare workers and students: Should we screen before vaccination? J Infect Public Health 2020;13(4):480–4. doi.org/10.1016/j.jiph.2020.01.309

Jung J, Kim SK, Kwak SH, Hong MJ, Kim SH. Seroprevalence of measles in healthcare workers in South Korea. Infect Chemother 2019;51(1):58–61. doi.org/10.3947/ic.2019.51.1.58

Benjamanukul S, Traiyan S, Kerddonfak S, Pratedrat P, Poovoravan Y. Comparison of diagnostic accuracy of self-reported varicella history with serum anti-varicella-zoster virus igg among hospital healthcare workers, samut sakhon province, thailand (September-october 2020). Southeast Asian J Trop Med Public Health 2021;52(4):547–56.

Camilloni B, Stracci F, Lio MC De, Mencacci A, Cenci E, Bozza S. Measles immunity in healthcare workers of an Italian hospital. J Infect Public Health 2020;13(8):1123–5. doi.org/10.1016/j.jiph.2020.04.001

Anugulruengkitt S, Puthanakit T, Siengboon S, Paitoonpong L, Kowitdamrong E, Pancharoen C, et al. Prevalence and characteristics of pediatric healthcare workers without immunity to varicella zoster virus. Jpn J Infect Dis 2017;70(2):216–8. doi.org/10.7883/yoken.JJID.2016.227

Wangsan K, Chaiear N, Krisorn P, Soonthornvinit W. Varicella Zoster immunity amongst new health personnel in a university hospital in northeastern Thailand. J Med Assoc Thail [Internet]. 2019 Jan 1 [Cited Nov 1, 2022];102(1):7. Available from: http://www.jmatonline.com/index.php/jmat/article/view/9842

Assavanopakun P, Chaiear N. Measles immunity among new health personnel at a Faculty of Medicine in Khon Kaen province, Thailand, 2019. Outbreak, Surveillance, Investig Response J 2020;13(1):26–32.

Jongkumchok W, Chaiear N, Soonthornvinit W, Lerdruampattana S. Immunity to hepatitis B virus as a fitness for duty program for health workers at the university hospital in Thailand. J Med Assoc Thail 2019;102(1):21–6.

Dinleyici EC, Borrow R, Safadi MAP, van Damme P, Munoz FM. Vaccines and routine immunization strategies during the COVID-19 pandemic. Hum Vaccines Immunother. 2021;17(2):400–7. doi.org/10.1080/21645515.2020.1804776

Botelho-Nevers E, Cassir N, Minodier P, Laporte R, Gautret P, Badiaga S, et al. Measles among healthcare workers: A potential for nosocomial outbreaks. Eurosurveillance. 2011;16(2):1–5. doi.org/10.2807/ese.16.02.19764-en

Basireddy P, Avileli S, Beldono N, Gundela S. Evaluation of immune response to hepatitis B vaccine in healthcare workers at a tertiary care hospital. Indian J Med Microbiol 2018;36(3):397–400. doi.org/10.4103/ijmm.IJMM_17_431

Suwanpakdee D, Laohapand C, Moolasart V, Lomtong P, Krairojananan N, Srisawat P, et al. Serosurveillance of varicella and hepatitis B infection after reported cases in medical students and the relationship between past varicella disease history and immunity status. J Med Assoc Thai 2012;95(Suppl 5):80–5.

Published

2023-04-26

How to Cite

1.
Wipahut K, Soonthornvinit W, Chaiear N. The Proportion of Hepatitis B virus, Measles, and Varicella Immunity Among New Healthcare Personnel at Faculty of Medicine Khon Kaen University, Thailand. SRIMEDJ [Internet]. 2023 Apr. 26 [cited 2024 May 10];38(2):161-7. Available from: https://li01.tci-thaijo.org/index.php/SRIMEDJ/article/view/257115

Issue

Section

Original Articles