Survival of Oral Cancer Patients After Diagnosis in Roi-Et Hospital, Roi-Et Province
Keywords:
oral cancer, survival rate, lip cancerAbstract
Background and Objective: The incidence of new cases and mortality from oral cancer (OC) has been increasing. To date, no studies have been conducted at Roi Et Hospital regarding prognostic factors and survival rates among oral cancer patients. Consequently, this study objectives to examine the factors and survival rates of oral cancer patients following diagnosis who received treatment at Roi Et Hospital.
Methods: This is a retrospective cohort study utilizing retrospective data collection from the Roi Et cancer registry between 2015-2021 for all new oral cancer cases with ICD-O, codes C00.0-C06.9. Vital status was followed up until 2024. Survival rates were analyzed using the Kaplan-Meier method, and factors affecting survival were analyzed using Cox regression.
Result: Among 433 OC cases, 316 deaths occurred, representing a mortality rate of 26.7 per 100 person-years (95%CI: 23.9 – 29.9). The median survival time was 1.45 years (95%CI: 1.18 – 1.97). The survival rates at 1, 3, 5, 7, and 9 years were 57.9% (95%CI: 53.17 – 62.46), 38.6% (95%CI: 33.98 - 43.13), 30.9% (95%CI: 26.53 – 35.41), 24.2% (95%CI: 19.76 – 28.90) and 20.5% (95%CI: 15.81 – 25.73), respectively. Regarding lip cancer and surgical treatment, after controlling for age and disease stage, surgery was found to significantly affect survival in lip cancer patients (adjusted HR = 0.44, 95% CI: 0.22 – 0.86).
Conclusion: The 5-year survival rate of oral cancer patients after diagnosis at Roi Et Hospital was low. Surgical treatments was found to be associated with survival outcomes in lip cancer patients. Therefore, treating physicians should consider surgical factors for appropriate treatment and further research should focus on varies treatments to enhance prolonged survival rates.
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