Quality of Life of Patient with Major Depressive Disorder at Psychiatric Out-Patient Services in Srinagarind Hospital
DOI:
https://doi.org/10.64960/srimedj.v40i5.267545Keywords:
quality of life, major depressive disorder, WHOQOL-BREF-THAIAbstract
Background and Objective: Patients with major depressive disorder (MDD) experience significantly deteriorated quality of life (QOL), causing numerous negative impacts across various domains. The objectives of this study were to explore the QOL among patients with MDD in domains of physical, psychological, social relationships, and environment and to investigate factors associated with QOL scores in MDD.
Methods: A retrospective descriptive study among the first-visited MDD patients aged 15–60 was conducted between June 2020 and June 2021 at psychiatric outpatient services in Srinagarind Hospital. The instruments used in the study included a general information questionnaire, the 9-question depressive symptoms screening (9Q), the 8-question suicidal risk evaluation (8Q), and the World Health Organization Quality of Life Brief–Thai (WHOQOL-BREF-THAI). The variables that statistically significant associated with QOL scores were included in the multiple linear regression model to analyse the predictive factors for QOL in MDD.
Results: Out of 96 MDD patients, 68 (70.8%) had overall QOL at a moderate level, and 23 (24.0%) had poor QOL. The QOL in the psychological domain was more frequently scored at a poor level compared to other domains in most MDD patients (53.1%). Depressive severity (9Q) and suicidal risk (8Q) scores were significantly negatively associated with QOL scores (β=-1.120, p<0.001 and β=-0.310, p<0.017). However, results from the multiple linear regression analysis showed that depressive severity was the only significant predictive factor for QOL level in MDD (β=-1.220, p<0.001; adjusted R2=0.310, F(2,91)=21.846, p<0.001).
Conclusion: Most of the MDD patients had overall QOL at a moderate level and the psychological domain of QOL was scored at a poor level more than others. The severity of depressive symptoms was the significant predictive factor for QOL level in MDD.
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