Effects of a Supportive and Educational Program on Knowledge of Self-Care Behaviors and International Normalized Ratio in Patients Following Surgical Artifical Cardiac Valve Replacement Therapy
-
DOI:
https://doi.org/10.64960/srimedj.v41i1.269457Keywords:
supportive and educational program, knowledge, self-care behaviors, international normalized ratio (INR)Abstract
Background and Objectives: Knowledge and preventive behaviors for complications after mechanical valve replacement are important indicators of patient-care outcomes. A supportive and educational program may help improve these outcomes. This study aimed to evaluate the effect of a supportive education program on knowledge, self-care behavior, and coagulation control (international normalized ratio, INR) in patients following mechanical valve replacement.
Methods: This quasi-experimental study used a two-group pre- and post-test design. A total of 54 participants who had undergone mechanical valve replacement for at least 5 years and whose INR was outside the therapeutic range, and who attended the cardiovascular thoracic surgical outpatient clinic at Srinagarind Hospital between September 2024 and July 2025, were enrolled. They were divided into an intervention group (n = 27) and a control group (n = 27). The intervention group received a 12-week supportive education program based on Orem’s self-care theory, while the control group received standard care. Data were collected via questionnaires assessing knowledge and self-care behaviors, and via measurements of INR. Analyses included descriptive statistics and inferential testing with generalized estimating equations (GEEs) and Bonferroni-adjusted multiple comparisons.
Results: The intervention group achieved significantly higher mean knowledge scores than baseline and the control group (mean difference = 4.33; 95% CI: 3.17-5.50; p < 0.001). Their self-care behaviors mean difference was 3.33 (95% CI: 1.49-5.18; p < 0.001) compared with baseline; however, the difference versus the control group was not statistically significant. In addition, 55.56% of the intervention group achieved INR values within the therapeutic range, compared with the control group, though this difference was not statistically significant (p = 0.655).
Conclusion: A supportive and educational program for self-care significantly increased knowledge and improved self-care behavior; it also increased the proportion of patients whose INR returned to the therapeutic range, although this latter improvement did not reach statistical significance.
References
Mitprachapranee C, Wongbuddha C, Chanmayka T. Modified bentall operation for the replacement of aortic root and ascending aorta: 5-year experience. Srinagarind Med J 2019;34(2):205–10.
Cardiac surgery statistics in Thailand [Internet]. The society of thoracic surgeons of Thailand. [cited Oct 3, 2025]. Available from: https://www.thaists.or.th/download-category/statistics-on-heart-surgery-in-thailand/.
Cardiac surgery statistical in Srinagarind Hospital 2021- 2023. 1981 Statistical of the surgical outpatient clinic, Division of Outpatient Nursing, Srinagarind Hospital.
Martins AS, Monteiro C, Duarte AP. Risks of oral anticoagulants: Analysis of adverse drug reactions reported to the Portuguese National Pharmacovigilance System. Pharmacol Res Perspect 2024;12(5):e1235 doi:10.1002/prp2.1235.
Poowaruttanawiwit P, Sonthisombut P, Sakunrag I, Rattanamanee K, Kunjara-Na-Avudhya R, Rimpanit S, et al. Food-warfarin interaction: facts and fictions. Thai Journal of Pharmacy Practice 2022;14(3):507–21.
Writing Committee Members, Otto CM, Nishimura RA, Bonow RO, Carabello BA, Erwin JP, et al. 2020 ACC/AHA guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American heart association joint committee on clinical practice guidelines. J Am Coll Cardiol 2021;77(4):e25–197. doi:10.1016/j.jacc.2020.11.01.
Khan RA, Shah BA, Noreen N, Khan RA, Ghani N. Effect of health education on knowledge regarding post-operative care among patients with mechanical valve replacement: a quasi-experimental study. Asian Journal of Research in Nursing and Health 2020;3(1):33-41.
Janampon J, Boonshuyar C, Ivanovitch K, Compliance to warfarin among cardiovascular disease patients, King Narai Hospital, Lopburi province. Journal of Medical and Public Health Region 4. 2023;13(3):59–70.
Srison P, Hachuck W, Ratchapakdee P, Uppasarn W,. Health literacy and self-care behavior among post valvular heart surgery patients. Journal of Nurses Association of Thailand Northern Office 2019;25(1):1–13.
Thongkao S, Kimsungnoen N, Namjuntra R. Effects of educative-supportive program on self-care behaviors and blood pressure levels among young adult patients with uncontrolled hypertension. Thai Journal of Cardio-Thoracic Nursing 2021;32(2):73–88.
Cheumthonh P, Kimsungnoen N, Namjuntra R. The effects of educative supportive program on self care behaviors and HbA1c in persons newly diagnosed with type 2 diabetes. Journal of Nursing Science & Health 2020;43(1):78–86.
Orem DE (Dorothea E, Taylor SG, Renpenning KM. Nursing: concepts of practice [Internet]. St. Louis: Mosby; 2001 [cited 2025 Oct 3]. 570. Available from: http://archive.org/details/nursingconceptso00dort
Wonggom P, Tadpinij S, Taksinachanekij S. Effect of self-management program on blood coagulation in patients with post cardiac valvular replacement. Graduate research conference. Khon Kaen University, 2013:755-66.
Schnittman SR, Itagaki S, Toyoda N, Adams DH, Egorova NN, Chikwe J. Survival and long-term outcomes after mitral valve replacement in patients aged 18 to 50 years. J Thorac Cardiovasc Surg 2018;155(1):96-102.e11.
Pomountip O. Self‑care behavior among working‑aged people in the primary care Muangya 4 Hau‑ta‑lay, Mueang district, Nakhon Ratchasima province. Burapha Journal of Medicine 2020;7(2):65‑76.
Potharin W, Thamnong C, Panpruek W. Factors influencing health-promoting behaviors among patients after prosthetic heart valve replacement. J Nurs Health Care 2014;32(1):31–39.
Li D, Liu P, Zhang H, Wang L. The effect of phased written health education combined with healthy diet on the quality of life of patients after heart valve replacement. J Cardiothorac Surg 2021;16(1):183. doi:10.1186/s13019-021-01437-7.
Kaewnguen N, Visudhtibhan PJ, Visudhtibhan A. Effects of an epilepsy control program via the line application on health literacy and health behavior in patients with epilepsy. Nursing Research and Innovation Journal 2022;28(1):109–26.
Havrda DE, Mai T, Chonlahan J. Enhanced antithrombotic effect of warfarin associated with low-dose alcohol consumption. Am J Geriatr Pharmacother 2005;3(4):297-300. doi:10.1592/phco.25.2.303.
Chawarat S, Ubahad C. Factors affecting INR values in warfarin users, Benchalak Chaloem Phrakiat 80th Pansa Hospital. Journal of Environmental and Community Health 2022;7(1):137-146.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Srinagarind Medical Journal

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
