Prevalence and Factors Associated with Abnormal Uterine Bleeding among Reproductive-Aged Women at Kaset Wisai Hospital : Retrospective Descriptive Study
DOI:
https://doi.org/10.64960/srimedj.v40i5.268629Keywords:
abnormal uterine bleeding, prevalence, risk factors, reproductive-age women, body mass indexAbstract
Background and Objective: Abnormal uterine bleeding (AUB) is a significant global health concern affecting reproductive-age women. Understanding its prevalence and risk factors is critical for targeted interventions. To determine the prevalence and identify risk factors associated with AUB among reproductive-age women seeking care at Kaset Wisai Hospital, Thailand.
Methods: A retrospective descriptive study was conducted using medical records of 281 eligible reproductive-age (15-49-years-old) women treated between October 1, 2022, and September 30, 2024. Data were analyzed using descriptive statistics and multivariate logistic regression
Results: The prevalence of abnormal uterine bleeding among women of reproductive age (15–49 years) was 75.1% (95% CI: 70.00–80.15). Statistically significant associations (p < 0.05) were observed with obesity, defined as body mass index (BMI ≥ 35 kg/m²) (AOR = 3.53; 95% CI: 1.61–7.73). In contrast, endometriosis was identified as a protective factor against abnormal uterine bleeding (AOR = 0.28; 95% CI: 0.15–0.54).
Conclusion: The findings of this study highlight the significance of body mass index as factors associated with abnormal uterine bleeding. These results underscore the importance of accurate etiological diagnosis to support effective assessment and management of abnormal uterine bleeding among reproductive-aged women at risk.
References
Kaset Wisai Hospital. Annual Operational Results Report for Fiscal Year B.E.2023. Strategic Affairs Group: Roi Et; 2023.
Munro MG, Critchley HOD, Fraser IS. The two FIGO systems for normal and abnormal uterine bleeding symptoms and classification of causes of abnormal uterine bleeding in the reproductive years: 2023 revisions. Int J Gynaecol Obstet 2023;143(3):393-408. doi:10.1002/ijgo.12666.
Matthews ML. Abnormal uterine bleeding in reproductive-aged women. Obstet Gynecol Clin North Am 2015;42(1):103-15. doi:10.1016/j.ogc.2014.09.006.
Stewart EA, Cookson CL, Gandolfo RA, Schulze-Rath R. Epidemiology of uterine fibroids: a systematic review. BJOG 2017;124(10):1501-12. doi:10.1111/1471-0528.14640.
Cicinelli E, Bettocchi S, de Ziegler D, Loizzi V, Cormio G, Marinaccio M, et al. Chronic endometritis, a common disease hidden behind endometrial polyps in premenopausal women: first evidence from a case-control study. J Minim Invasive Gynecol 2019;26(7):1346-50. doi:10.1016/j.jmig.2019.01.012.
Lopez LM, Grey TW, Stuebe AM, Chen M, Truitt ST, Gallo MF. Combined hormonal versus nonhormonal versus progestin-only contraception in lactation. Cochrane Database Syst Rev 2023;2023(3):CD003988. doi:10.1002/14651858.CD003988.pub2.
ESHRE Guideline Group on RPL; Atik RB, Christiansen OB, Elson J, Kolte AM, Lewis S, et al. ESHRE guideline: recurrent pregnancy loss. Hum Reprod Open 2023;2023(1):hoac002. doi:10.1093/hropen/hoac002.
Hisham A, Bukhari ME , Alkhamis WH, Albadawi IA, Shukri MA , Angion S, et al. Iron deficiency anemia and uterine disorders: Impact on surgical management. Journal of Endometriosis and Uterine Disorders 2025;10:100112. doi:10.1016/j.jeud.2025.100112.
Seid A, Bulto GA, Yesuf A, Yimer A, Ahmed H, Muse TB. et al. Magnitude and determinants of abnormal uterine bleeding among reproductive-age women in Kombolcha Rejiopolitan Administrative town, northeast Ethiopiaethiopia: a FIGO-based cross‑sectional study (2023). Front Reprod Health 2025;7:1559105. doi:10.3389/frph.2025.1559105.
Abebe M, Melaku G, Hareru HE, Tebeje TM. Abnormal uterine bleeding and its associated factors among reproductive-age women who visit the gynecology ward in Dilla University General Hospital, Southern Ethiopia, 2022. BMC Womens Health 2024;24(1):281. doi:10.1186/s12905-024-03128-6.
Zafar M, Sadeeqa S, Latif S, Afzal H. Pattern and prevalence of menstrual disorders in adolescents. International Journal of Pharmaceutical Sciences and Research 2018;9(5):2088-99. doi:10.13040/IJPSR.0975-8232.9(5).2088-99.
Nyirenda T, Nyagumbo E, Murewanhema G, Mukonowenzou N, Kagodora SB, Mapfumo C, et al. Prevalence of dysmenorrhea and associated risk factors among university students in Zimbabwe. Women's Health, 2023;19:17455057231189549. doi:10.1177/17455057231189549.
Akalyaa K, Shakuntala PN, Renuka R. Correlation of body mass index and abnormal uterine bleeding in premenopausal women. Int J Reprod Contracept Obstet Gynecol 2020;9(11):4640-7. doi:10.18203/2320-1770.ijrcog20204826.
Nouri M, Tavakkolian A, Mousavi SR.Association of dysfunctional uterine bleeding with high body mass index and obesity as a main predisposing factor. Diabetes Metab Syndr 2014;8(1):1-2. doi:10.1016/j.dsx.2013.10.013.
Dynnik VO, Shcherbina SNA, Dynnik DAA. The relationship between the individual components of the reproductive system and energy metabolic hormones in abnormal uterine bleeding in adolescence. [cited January 15, 2025] Available from: https://kku.world/xqwh9b. doi:10.18565/aig.2018.2.102-107.
World Health Organization. Guidelines for the management of abnormal uterine bleeding in reproductive-aged women. Geneva: WHO; 2023.
Masood R, Dev V, Gee M, Finch K, Fletcher DM Bamidele O, et al. How should abnormal uterine bleeding be managed in people with bleeding disorders: A systematic review of the literature and thematic synthesis. Research and Practice in Thrombosis and Haemostasis, 2025. doi:10.1016/j.rpth.2025.103167.
International Federation of Gynecology and Obstetrics. FIGO recommendations on the prevention and management of obesity-related reproductive disorders. Int J Gynaecol Obstet 2024;165(1):12-25. doi:10.1002/ijgo.15342.
Ferenczy A. Pathophysiology of endometrial bleeding. Maturitas, 2003;45(1): 1-14. doi:10.1016/s0378-5122(03)00068-9.
Reis FM, Bloise E, Ortiga-Carvalho TM. Hormones and pathogenesis of uterine fibroids. Best Pract Res Clin Obstet Gynaecol 2016;34:13-24. doi:10.1016/j.bpobgyn.2015.11.015.
World Health Organization. Guidelines for the management of endometriosis-associated symptoms. Geneva: WHO; 2023.
Dolmans MM, Cacciottola L, Donnez J. Conservative management of uterine fibroid-related heavy menstrual bleeding and infertility: time for a deeper mechanistic understanding and an individualized approach. J Clin Med 2021;10(19):4389. doi: 10.3390/jcm10194389.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Srinagarind Medical Journal
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
