RNA Interference Technology and Its Potential Use in Functional Genomic Analysis

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Published: Mar 30, 2018
Keywords:
RNAi, functional genomic analysis

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Song Ying Qi
Department of Life Science, Harbin Institute of Technology, Harbin, China
Yang Qian
Department of Life Science, Harbin Institute of Technology, Harbin, China

Abstract

RNA interference (RNAi) refers to the introduction of homologous double standard RNA (dsRNA) to specifically target a gene’s product, resulting in null or hypomorphic phenotypes. RNAi is highly gene specific, so it is much more effective than either sense or antisense RNA for producing gene interference activity. RNAi has recently emerged as a powerful reverse genetic tool to silence gene expression in the field of functional genomic analysis, including plants, Caenorhabditis elegans, and Drosophila for it allows researchers to study the effects of genomic loss of function in developing embryos without the complications of the gene knockout method.


Keywords: RNAi, functional genomic analysis


Corresponding author: E-mail: cast@kmitl.ac.th

Article Details

How to Cite
Qi, S. Y., & Qian, Y. (2018). RNA Interference Technology and Its Potential Use in Functional Genomic Analysis. CURRENT APPLIED SCIENCE AND TECHNOLOGY, 4(1), 251–259. retrieved from https://li01.tci-thaijo.org/index.php/cast/article/view/151928
Issue
Vol. 4 No. 1 (2004)
Section
Review Ariticle

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