Kinetics Study of Antibacterial Activity of Cajuput Oil (Melaleuca cajuputi) on Escherichia coli, Staphylococcus aureus, and Bacillus cereus

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Rustam Musta*
Laily Nurliana
Lili Darlian
La Rudi


The kinetics of antibacterial activity of cajuput oil (Melaleuca cajuputi) to E. coli, B. cereus, and S. aureus were investigated. The aim of this study was to determine the reaction orders of cajuput oil as an antibacterial agent. The extraction of cajuput oil was conducted by water-steam distillation. The yield was 0.88%. GC-MS analysis showed that the cajuput oil contained β-ocimene (19.35%), 1.8-cineole (17.67%), limonene (12.09%), β-caryophyllene (9.51%), γ-terpinene (8.93%), 2-β-pinene (8.85%), α-terpinolene (4.96%), α-humulene (4.10%), α-terpineol (2.83%), and p-cymene (2.33%). The extract showed antibacterial activity to E. coli, B. cereus, and S. aureus, with the reaction orders of 0.4460, 0.8235 and 0.6928, respectively

Keywords: cajuput oil; antibacterial; E. coli; B. cereus; S. aureus; kinetics; Melaleuca cajuputi

*Corresponding author: Tel.: +6281227053886



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