ASPARAGINASE PRODUCTION BY ENDOPHYTIC FUNGI ISOLATED FROM SOME THAI MEDICINAL PLANTS

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Published: Nov 1, 2007
Keywords:
endophytic fungi Thai medicinal plants asparaginase

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T. Theantana*
The Graduated School, Chiang Mai University, Chiang Mai, Thailand
K.D. Hyde
Centre for Research in Fungi Diversity, Department of Ecology & Biodiversity, Hong Kong University, SAR PR China
S. Lumyong
Department of Biotechnology, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand

Abstract

Asparaginase is an important enzyme used as an anti-cancer compound. Five Thai medicinal plants, Hiptage benghalensis, Betula alnoides, Adenanthera microsperma, Eupatorium odoratum and Houttuynia cordata were used for fungal isolation by triple surface sterilization method. One hundred and seventeen isolates of endophytic fungi were evaluated for asparaginase production using qualitative and quantitative analyses. Twenty-five isolates demonstrated pink zone around their colonies in the agar plate assays. Fungal isolates from H. benghalensis and E. odoratum were highly active when tested with the spectrophotometric method. The endophytic fungi with high activity are proposed as a possible asparaginase source to manage cancer cells. 


Keywords: endophytic fungi, Thai medicinal plants, asparaginase


Corresponding author: E-mail: scboi009@chiangmai.ac.th

Article Details

How to Cite
Theantana*, T., Hyde, K., & Lumyong, S. (2007). ASPARAGINASE PRODUCTION BY ENDOPHYTIC FUNGI ISOLATED FROM SOME THAI MEDICINAL PLANTS. CURRENT APPLIED SCIENCE AND TECHNOLOGY, 7(1-1), 13–18. retrieved from https://li01.tci-thaijo.org/index.php/cast/article/view/86787
Issue
Vol. 7 No. 1-1 (2007)
Section
Original Research Articles

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Author Biography

T. Theantana*, The Graduated School, Chiang Mai University, Chiang Mai, Thailand

The Graduated School, Chiang Mai University, Chiang Mai, Thailand

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