PHYTOCHEMICAL SCREENING ANTIOXIDANT ACTIVITIES α-AMYLASE AND α-GLUCOSIDASE INHIBITORY ACTIVITIES OF Cnidoscolus aconitifolius EXTRACTS
Keywords:
Phytochemical Screening, Antioxidant activities, α-Amylas, α-Glucosidase, Cnidoscolus aconitifoliusAbstract
The aim of present study is to phytochemical screening antioxidant activities α-Amylase and α-Glucosidase Inhibitory Activities of Cnidoscolus aconitifolius extract both fresh and dried. In this study, The Phytochemical screening of Cnidoscolus aconitifolius leaves extracts from both fresh and dried that present of flavonoids, coumarins, tannins, phlobatannins, terpenoids, steroids, and cardiac glycosides. The extracts of Cnidoscolus aconitifolius leaves of dried have the highest total phenolic content was 79.34 mg GAE/g extract, total flavonoids content the highest of 35.61 mg QE/g extract. The antioxidant activity using DPPH free radical scavenging method extracts of Cnidoscolus aconitifolius leaves from dried extracts is the highest antioxidant activity with IC50 values of 11.58 2.19 mg/mL. In addition, the extracts of Cnidoscolus aconitifolius leaves from dried showed most anti-α-glucosidase and anti-α-amylase activities activity with IC50 values of 10.24 2.45 and 9.281.09 mg/mL, respectively. These results suggest the potential of Cnidoscolus aconitifolius leaves as diabetic mellitus medicine or food supplement.
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