Acute Ocular Blindness Associated with Chronic Renal Failure and Canine Monocytic Ehrlichiosis in a Dog: A Case Report

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Thanate Anusaksathien
Jetsada Rungpupradit
Puttipong Thermtong
Latthasit Issararak


A 12-year old male poodle dog was present with a history of conjunctivitis. Three days later, the dog bumped into objects. Corneal edema and buphthalmos was found in the left eye. Acute blindness of both eyes was diagnosed from negative of all three reflexes (menace response, dazzle reflex and pupillary light reflex). Moderated conjunctivitis, panuveitis were found from ocular examination. Indolent ulcer in the left eyes and glaucoma were diagnosed from fluorescein staining and high intraocular pressure about 32 mmHg in the left eye respectively. Ocular ultrasonography found complete retinal detachment and vitreous hemorrhage. Beside ocular diseases, chronic renal failure stage 2, systemic hypertension about 300 mmHg, proteinuria and canine monocytic ehrlichiosis were concurrently diagnosed in this dog. The dog was prescribed medical treatment with tropical ocular medication, systemic medication for ehrlichiosis, blood pressure control and the management of proteinuria. As the treatment‘s result, systemic hypertension, intraocular pressure and certain ocular lesion were improved. However, the dog could not be regained vision afterward.  In this case, complete retinal detachment causes acute blindness was suspected induce by systemic hypertension which is a complication of chronic renal failure and we believed canine monocytic ehrlichiosis played important role for develop chronic renal failure and ocular diseases in this dog.


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Acierno, M.J., S. Brown, A. E. Coleman, R. E. Jepson, M. Papich, R. L. Stepien, and H. M. Syme. 2018. ACVIM consensus statement: Guidelines for the identification, evaluation, and management of systemic hypertension in dogs and cats. J. Vet. Intern. Med. 1-20. (in Thai)
Aroch, I., R. Ofri, and G. A. Sutton. 2013. Ocular Manifestation of Systemics Disease. In: Slatter’s Fundamentals of Veterinary Ophthalmology. 5th ed. Missouri: Elsevier Inc. 394-406. (in Thai)
Buoncompagni, S. and H. M. Bowles. 2013. Treatment of systemic hypertension associated with kidney disease. Compendium. 2013: 1-6. (in Thai)
Cullen, C. L. and A. A. Webb. 2013. Ocular manifestations of systemic disease. In: Slatter’s Fundamentals of Veterinary Ophthalmology. 5th ed. Missouri: Elsevier Inc. 299-333. (in Thai)
Harrus, S., T. Wanner, and T. M. Neer. 2012. Ehrlichia and anaplasma infections. In: Infectious disease of the dog and cat. 4th ed. Elsevier. Missouri. P.227-237. (in Thai)
Jenkins, S., J. K. Ketzis, J. Dundas, and D. Scorpio. 2018. Efficacy of Minocycline in Naturally Occurring Nonacute Ehrlichia canis Infection in Dogs. J. Vet. Intern. Med. (32): 217-221. (in Thai)
LeBlanc, N. L., R. L. Stepien, and E. Bentley. 2011. Ocular lesions associated with systemic hypertension in dogs: 65 cases (2005–2007). J. Am. Vet. Med. Assoc. 238(7). 915–921. (in Thai)
Leiva, M., C. Naranjo, and M. T. Peña. 2005. Ocular signs of canine monocytic ehrlichiosis: a retrospective study in dogs from Barcelona, Spain. Veterinary Ophthalmology. (8): 387-393. (in Thai)
Ofri, R. 2013. Retina. In: Slatter’s Fundamentals of Veterinary Ophthalmology. 5th ed. Missouri: Elsevier Inc. 299-333. (in Thai)
Ohad, D. G. 2017. Treatment of systemic hypertension. In: Textbook of veterinary internal medicine. 8th ed. Elsevier. Missouri. P.1729-1740. (in Thai)
Plummer, C. E. 2016. Diagnosing acute blindness in dogs. An Official Journal of the NAVC. November/December 2016: 1-6. (in Thai)
Steele, K. A., S. Sisler, and P. A. Gerding. 2012. Outcome of retinal reattachment surgery in dogs: a retrospective study of 145 cases. Veterinary Ophthalmology. (2012): 1-6. (in Thai)