Efficacy of crude extract of thai herbal to Inhibit Dermatophyte DT01 isolated from Fighting Cock
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Abstract
This research aimed to study antifungal activity of 7 Thai herbal (Alpinia galanga, Zingiber officinale, Ocimum sanctum L., Allium sativum L., Cymbopogon citrates, Curcuma longa and Boesenbergia pandurate) ethanol extracts against Dermatophyte DT01 by agar well diffusion method. The results showed that all Thai herbal extracts inhibited DT01. The crude extracts of Allium sativum L. showed the highest DT01 inhibitory effect, with 58% inhibition compared to the positive control results by using Itraconazole, which 53% inhibition. Other herbs, including Alpinia galanga, Zingiber officinale, Ocimum sanctum L., Cymbopogon citrates, Curcuma longa and Boesenbergia pandurate showed the high DT01 inhibitory effect as follows: 43, 54, 42, 32, 56 and 45, respectively. The 7 extracted herbs were grouped to test antifungal activity (DT01). The results showed that the crude extracts the best DT01 inhibition (62%) compared to all groups and compared them with the use of coarse extracts from single herbs.
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References
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