Composition of phenolic compounds and antibacterial activities of Paederia pilifera Hook. f. leaf extract

Authors

  • Pornpun siramon King Mongkut’s University of Technology Thonburi (Ratchaburi Campus)
  • Rattiya Waeonukul Pilot Plant Development and Training Institute, King Mongkut's University of Technology Thonburi
  • Supitchaya Laothong Pilot Plant Development and Training Institute, King Mongkut's University of Technology Thonburi

Keywords:

Antibacterial activity, Flavonoids, Paederia pilifera, Phenolic compounds

Abstract

In this study, phenolic compounds were extracted from Paederia pilifera Hook. f. leaves. The phenolic compositions of crude extract were determined by Liquid Chromatography - Mass Spectrometry (LC-MS). Phenolic acids and flavonoids were identified as the major phenolic compound compositions in the crude extract.  Furthermore, crude extract was performed to evaluate the antibacterial activities against 3 human pathogenic strains: Staphylococcus aureus DMST 8840, Staphylococcus epidermidis DMST 15505 and Methicillin-resistant Staphylococcus aureus (MRSA) DMST 20651. The results revealed that P. pilifera crude extract exhibited antibacterial activities against all tested bacterial strains with a minimal inhibitory concentration (MIC) value of 25.60 mg/mL and minimal bactericidal concentration (MBC) value of 51.20 mg/mL for S. aureus and MRSA, and 25.60 mg/mL for S. epidermidis.

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Published

2022-04-30

How to Cite

1.
siramon P, Waeonukul R, Laothong S. Composition of phenolic compounds and antibacterial activities of Paederia pilifera Hook. f. leaf extract. Health Sci Tech Rev [Internet]. 2022 Apr. 30 [cited 2024 Nov. 19];15(1):3-10. Available from: https://li01.tci-thaijo.org/index.php/journalup/article/view/248727

Issue

Vol. 15 No. 1 (2022): January - May

Section

Research articles

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